Metabolism Antibodies 2

Anti-AMPD3 Antibody (CAB6354)

(No reviews yet) Write a Review
SKU:
CAB6354
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-AMPD3 Antibody
Antibody SKU:CAB6354
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse kidney, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MALS SEPA EMPR QFPK LNIS EVDE QVRL LAEK VFAK VLRE EDSK DALS LFTV PEDC PIGQ KEAK EREL QKEL AEQK SVET AKRK KSFK MIRS QSLS LQMP PQQD WKGP PAAS PAMS PTTP VVTG ATSL PTPA PYAM PEFQ RVTI SGDY CAGI TLED YEQA AKSL AKAL MIRE KYAR LAYH RFPR ITSQ YLGH PRAD TAPP EEGL PDFH PPPL PQED PYCL DDAP PNLD YLVH MQGG ILFV YDNK KMLE HQEP HSLP YPDL
Gene ID:272
Uniprot:Q01432
Cellular Location:
Calculated MW:24kDa/71kDa/76kDa/88kDa/89kDa
Observed MW:89kDa
Synonyms:AMPD3
Background:This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
UniProt Protein Function:AMP deaminase plays a critical role in energy metabolism.
NCBI Summary:This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
UniProt Code:Q01432
NCBI GenInfo Identifier:399033
NCBI Gene ID:272
NCBI Accession:Q01432.1
UniProt Secondary Accession:Q01432,A0AUX0, B7Z2S2, B7Z763, B7Z877,
UniProt Related Accession:Q01432
Molecular Weight:71,222 Da
NCBI Full Name:AMP deaminase 3
NCBI Synonym Full Names:adenosine monophosphate deaminase 3
NCBI Official Symbol:AMPD3  
NCBI Protein Information:AMP deaminase 3
UniProt Protein Name:AMP deaminase 3
UniProt Synonym Protein Names:AMP deaminase isoform E; Erythrocyte AMP deaminase
Protein Family:AMP deaminase
UniProt Gene Name:AMPD3  
UniProt Entry Name:AMPD3_HUMAN
Anti-AMPD3 Antibody (CAB6354)Western blot analysis of extracts of various cell lines, using AMPD3 antibody (CAB6354) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products