Metabolism Antibodies 3

Anti-AMPD2 Antibody (CAB16247)

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SKU:
CAB16247
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-AMPD2 Antibody
Antibody SKU:CAB16247
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 657-798 of human AMPD2 (NP_631895.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 657-798 of human AMPD2 (NP_631895.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NSLF LSYH RNPL PEYL SRGL MVSL STDD PLQF HFTK EPLM EEYS IATQ VWKL SSCD MCEL ARNS VLMS GFSH KVKS HWLG PNYT KEGP EGND IRRT NVPD IRVG YRYE TLCQ ELAL ITQA VQSE MLET IPEE AGIT MSPG PQ
Gene ID:271
Uniprot:Q01433
Cellular Location:
Calculated MW:88kDa/92kDa/100kDa
Observed MW:Refer to figures
Synonyms:AMPD2, PCH9, SPG63
Background:The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:AMPD2: AMP deaminase plays a critical role in energy metabolism. Belongs to the adenosine and AMP deaminases family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Hydrolase; EC 3.5.4.6; Nucleotide Metabolism - purine

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: cytosol

Molecular Function:AMP deaminase activity; protein binding

Biological Process: IMP biosynthetic process; purine salvage

Disease: Pontocerebellar Hypoplasia, Type 9; Spastic Paraplegia 63, Autosomal Recessive

NCBI Summary:The protein encoded by this gene is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
UniProt Code:Q01433
NCBI GenInfo Identifier:12644375
NCBI Gene ID:271
NCBI Accession:Q01433.2
UniProt Secondary Accession:Q01433,Q14856, Q14857, Q16686, Q16687, Q16688, Q16729 Q5T693, Q5T695, B4DK50, B4DZI5, E9PNG0,
UniProt Related Accession:Q01433
Molecular Weight:88,288 Da
NCBI Full Name:AMP deaminase 2
NCBI Synonym Full Names:adenosine monophosphate deaminase 2
NCBI Official Symbol:AMPD2  
NCBI Official Synonym Symbols:PCH9; SPG63  
NCBI Protein Information:AMP deaminase 2
UniProt Protein Name:AMP deaminase 2
UniProt Synonym Protein Names:AMP deaminase isoform L
Protein Family:AMP deaminase
UniProt Gene Name:AMPD2  
UniProt Entry Name:AMPD2_HUMAN
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