Metabolism Antibodies 2

Anti-AMPD1 Antibody (CAB7876)

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SKU:
CAB7876
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-AMPD1 Antibody
Antibody SKU:CAB7876
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human AMPD1
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:HT-29, Mouse skeletal muscle, Mouse thymus, Mouse pancreas
Immunogen:A synthetic peptide of human AMPD1
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:270
Uniprot:P23109
Cellular Location:
Calculated MW:89kDa/90kDa
Observed MW:80kDa
Synonyms:AMPD1, MAD, MADA, MMDD
Background:Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
UniProt Code:P23109
NCBI GenInfo Identifier:384872309
NCBI Gene ID:270
NCBI Accession:P23109.2
UniProt Secondary Accession:P23109,Q5TF00, Q5TF02, A8K5N4, B2RAM1, F2Z3B3,
UniProt Related Accession:P23109
Molecular Weight:747
NCBI Full Name:AMP deaminase 1
NCBI Synonym Full Names:adenosine monophosphate deaminase 1
NCBI Official Symbol:AMPD1  
NCBI Official Synonym Symbols:MAD; MADA; MMDD  
NCBI Protein Information:AMP deaminase 1; AMPD; skeletal muscle AMPD; myoadenylate deaminase; adenosine monophosphate deaminase-1 (muscle); adenosine monophosphate deaminase 1 (isoform M)
UniProt Protein Name:AMP deaminase 1
UniProt Synonym Protein Names:AMP deaminase isoform M; Myoadenylate deaminase
Protein Family:AMP deaminase
UniProt Gene Name:AMPD1  
UniProt Entry Name:AMPD1_HUMAN
Anti-AMPD1 Antibody (CAB7876)Western blot analysis of extracts of various cell lines, using AMPD1 antibody (CAB7876) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s.
Anti-AMPD1 Antibody (CAB7876)Immunohistochemistry of paraffin-embedded human esophagus using AMPD1 antibody (CAB7876) (40x lens).
Anti-AMPD1 Antibody (CAB7876)Immunohistochemistry of paraffin-embedded rat brain using AMPD1 antibody (CAB7876) (40x lens).
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