Metabolism Antibodies 2

Anti-AMPD1 Antibody (CAB3584)

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SKU:
CAB3584
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Metabolism

Description

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Antibody Name:Anti-AMPD1 Antibody
Antibody SKU:CAB3584
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human AMPD1 (NP_001166097.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:A375, SKOV3, A-549, Mouse heart, Mouse lung, Rat skeletal muscle, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 50-260 of human AMPD1 (NP_001166097.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AEKV FASE VKDE GGRQ EISP FDVD EICP ISHH EMQA HIFH LETL STST EARR KKRF QGRK TVNL SIPL SETS STKL SHID EYIS SSPT YQTV PDFQ RVQI TGDY ASGV TVED FEIV CKGL YRAL CIRE KYMQ KSFQ RFPK TPSK YLRN IDGE AWVA NESF YPVF TPPV KKGE DPFR TDNL PENL GYHL KMKD GVVY VYPN EAAV SKDE PKP
Gene ID:270
Uniprot:P23109
Cellular Location:
Calculated MW:89kDa/90kDa
Observed MW:80kDa
Synonyms:AMPD1, MAD, MADA, MMDD
Background:Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
UniProt Code:P23109
NCBI GenInfo Identifier:384872309
NCBI Gene ID:270
NCBI Accession:P23109.2
UniProt Secondary Accession:P23109,Q5TF00, Q5TF02, A8K5N4, B2RAM1, F2Z3B3,
UniProt Related Accession:P23109
Molecular Weight:747
NCBI Full Name:AMP deaminase 1
NCBI Synonym Full Names:adenosine monophosphate deaminase 1
NCBI Official Symbol:AMPD1  
NCBI Official Synonym Symbols:MAD; MADA; MMDD  
NCBI Protein Information:AMP deaminase 1; AMPD; skeletal muscle AMPD; myoadenylate deaminase; adenosine monophosphate deaminase-1 (muscle); adenosine monophosphate deaminase 1 (isoform M)
UniProt Protein Name:AMP deaminase 1
UniProt Synonym Protein Names:AMP deaminase isoform M; Myoadenylate deaminase
Protein Family:AMP deaminase
UniProt Gene Name:AMPD1  
UniProt Entry Name:AMPD1_HUMAN
Anti-AMPD1 Antibody (CAB3584)Western blot analysis of extracts of various cell lines, using AMPD1 antibody (CAB3584) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-AMPD1 Antibody (CAB3584)Immunofluorescence analysis of NIH/3T3 cells using AMPD1 Rabbit pAb (CAB3584) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-AMPD1 Antibody (CAB3584)Immunofluorescence analysis of HeLa cells using AMPD1 Rabbit pAb (CAB3584) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-AMPD1 Antibody (CAB3584)Immunofluorescence analysis of C6 cells using AMPD1 Rabbit pAb (CAB3584) at dilution of 1:100. Blue: DAPI for nuclear staining.
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