Cell Biology Antibodies 14
Anti-AMOTL1 Antibody (CAB18112)
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- SKU:
- CAB18112
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-AMOTL1 Antibody |
| Antibody SKU: | CAB18112 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human AMOTL1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, MCF7, Mouse heart, Mouse lung, Mouse brain, Rat lung, Rat heart |
| Immunogen: | Recombinant protein of human AMOTL1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 154810 |
| Uniprot: | Q8IY63 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 107kDa |
 | Western blot - AMOTL1 Rabbit pAb (CAB18112) |
| Synonyms: | JEAP, AMOTL1 |
| Background: |
| UniProt Protein Function: | Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. |
| NCBI Summary: | The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q8IY63 |
| NCBI GenInfo Identifier: | 666335625 |
| NCBI Gene ID: | 154810 |
| NCBI Accession: | NP_001287936.1 |
| UniProt Secondary Accession: | Q8IY63,Q63HK7, Q8NDN0, Q8TEN8, Q8WXD1, Q96CM5, |
| UniProt Related Accession: | Q8IY63 |
| Molecular Weight: | 101,179 Da |
| NCBI Full Name: | angiomotin-like protein 1 isoform 2 |
| NCBI Synonym Full Names: | angiomotin like 1 |
| NCBI Official Symbol: | AMOTL1 |
| NCBI Official Synonym Symbols: | JEAP |
| NCBI Protein Information: | angiomotin-like protein 1 |
| UniProt Protein Name: | Angiomotin-like protein 1 |
| Protein Family: | Angiomotin-like protein |
| UniProt Gene Name: | AMOTL1 |
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