Anti-AMD1 Antibody (CAB8537)
- SKU:
- CAB8537
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AMD1
- Synonyms:
- ADOMETDC
- Synonyms:
- AMD
- Synonyms:
- SAMDC
Description
| Product Name: | AMD1 Rabbit pAb |
| Product Code: | CAB8537 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | AMD1, ADOMETDC, AMD, SAMDC |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human AMD1 (NP_001625.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, Mouse skeletal muscle, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human AMD1 (NP_001625.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RRFI LKTC GTTL LLKA LVPL LKLA RDYS GFDS IQSF FYSR KNFM KPSH QGYP HRNF QEEI EFLN AIFP NGAA YCMG RMNS DCWY LYTL DFPE SRVI SQPD QTLE ILMS ELDP AVMD QFYM KDGV TAKD VTRE SGIR DLIP GSVI DATM FNPC GYSM NGMK SDGT YWTI HITP EPEF SYVS FETN LSQT SYDD LIRK VVEV FKPG KFVT TLFV NQSS KCRT VLAS PQKI EGFK RLDC QSAM FNDY NFVF TSFA KKQQ QQQS |
| Gene ID: | 262 |
| Uniprot: | P17707 |
| Calculated MW: | 21kDa/38kDa |
| Observed MW: | 32KDa/42KDa |
| UniProt Protein Function: | AMD1: an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y.[provided by RefSeq, Jul 2010] |
| UniProt Protein Details: | Protein type:Amino Acid Metabolism - arginine and proline; Lyase; Amino Acid Metabolism - cysteine and methionine; EC 4.1.1.50 Chromosomal Location of Human Ortholog: 6q21 Cellular Component: cytosol Molecular Function:adenosylmethionine decarboxylase activity Biological Process: S-adenosylmethioninamine biosynthetic process; spermidine biosynthetic process; spermine biosynthetic process; polyamine metabolic process |
| NCBI Summary: | This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013] |
| UniProt Code: | P17707 |
| NCBI GenInfo Identifier: | 116241324 |
| NCBI Gene ID: | 262 |
| NCBI Accession: | P17707.2 |
| UniProt Secondary Accession: | P17707,Q5VXN4, Q5VXN6, Q9BWK4, E1P5F7, |
| UniProt Related Accession: | P17707 |
| Molecular Weight: | 21,301 Da |
| NCBI Full Name: | S-adenosylmethionine decarboxylase proenzyme |
| NCBI Synonym Full Names: | adenosylmethionine decarboxylase 1 |
| NCBI Official Symbol: | AMD1 |
| NCBI Official Synonym Symbols: | AMD; SAMDC; ADOMETDC |
| NCBI Protein Information: | S-adenosylmethionine decarboxylase proenzyme; S-adenosylmethionine decarboxylase 1 |
| UniProt Protein Name: | S-adenosylmethionine decarboxylase proenzyme |
| Protein Family: | S-adenosylmethionine decarboxylase proenzyme |
| UniProt Gene Name: | AMD1 |
| UniProt Entry Name: | DCAM_HUMAN |
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