| Background: | There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase. |
| UniProt Protein Function: | ALPPL2: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; EC 3.1.3.1; Cofactor and Vitamin Metabolism - folate biosynthesis; Phosphatase (non-protein) Chromosomal Location of Human Ortholog: 2q37 |
| NCBI Summary: | There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P10696 |
| NCBI GenInfo Identifier: | 145559564 |
| NCBI Gene ID: | 251 |
| NCBI Accession: | P10696.4 |
| UniProt Secondary Accession: | P10696,Q16727, Q53S81, Q96CM1, A8KAF2, |
| UniProt Related Accession: | P10696 |
| Molecular Weight: | 57,377 Da |
| NCBI Full Name: | Alkaline phosphatase, placental-like |
| NCBI Synonym Full Names: | alkaline phosphatase, placental like 2 |
| NCBI Official Symbol: | ALPPL2 |
| NCBI Official Synonym Symbols: | ALPG; GCAP; ALPPL |
| NCBI Protein Information: | alkaline phosphatase, placental-like |
| UniProt Protein Name: | Alkaline phosphatase, placental-like |
| UniProt Synonym Protein Names: | ALP-1; Alkaline phosphatase Nagao isozyme; Germ cell alkaline phosphatase; GCAP; Placental alkaline phosphatase-like; PLAP-like |
| Protein Family: | Alkaline phosphatase |
| UniProt Gene Name: | ALPPL2 |
| UniProt Entry Name: | PPBN_HUMAN |