Epigenetics & Nuclear Signaling Antibodies 1
Anti-ALKBH4 Antibody (CAB12593)
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- SKU:
- CAB12593
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-ALKBH4 Antibody |
| Antibody SKU: | CAB12593 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human ALKBH4 (NP_060091.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-302 of human ALKBH4 (NP_060091.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAAA AAET PEVL RECG CKGI RTCL ICER QRGS DPPW ELPP AKTY RFIY CSDT GWAV GTEE SDFE GWAF PFPG VMLI EDFV TREE EAEL VRLM DRDP WKLS QSGR RKQD YGPK VNFR KQKL KTEG FCGL PSFS REVV RRMG LYPG LEGF RPVE QCNL DYCP ERGS AIDP HLDD AWLW GERL VSLN LLSP TVLS MCRE APGS LLLC SAPS AAPE ALVD SVIA PSRS VLCQ EVEV AIPL PARS LLVL TGAA RHQW KHAI HRRH IEAR RVCV TFRE LSAE FGPG GRQQ ELGQ ELLR IALS FQGR PV |
| Gene ID: | 54784 |
| Uniprot: | Q9NXW9 |
| Cellular Location: | Cytoplasm, Midbody, Nucleus |
| Calculated MW: | 4kDa/33kDa |
| Observed MW: | Refer to figures |
| Synonyms: | ALKBH4, ABH4 |
| Background: |
| UniProt Protein Function: | ALKBH4: Probable dioxygenase that requires molecular oxygen, alpha-ketoglutarate and iron. Belongs to the alkB family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 1.14.11.- Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: cytoplasm; midbody; nucleus Molecular Function:metal ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; actin binding; demethylase activity Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; actomyosin structure organization and biogenesis; protein amino acid demethylation |
| UniProt Code: | Q9NXW9 |
| NCBI GenInfo Identifier: | 74734701 |
| NCBI Gene ID: | 54784 |
| NCBI Accession: | Q9NXW9.1 |
| UniProt Related Accession: | Q9NXW9 |
| Molecular Weight: | |
| NCBI Full Name: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 |
| NCBI Synonym Full Names: | alkB homolog 4, lysine demethylase |
| NCBI Official Symbol: | ALKBH4 |
| NCBI Official Synonym Symbols: | ABH4 |
| NCBI Protein Information: | alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 |
| UniProt Protein Name: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 |
| UniProt Synonym Protein Names: | Alkylated DNA repair protein alkB homolog 4 |
| UniProt Gene Name: | ALKBH4 |
| UniProt Entry Name: | ALKB4_HUMAN |
 | Immunofluorescence analysis of A549 cells using ALKBH4 antibody (CAB12593). Blue: DAPI for nuclear staining. |
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