Cell Biology Antibodies 13

Anti-ALG5 Antibody (CAB17693)

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SKU:
CAB17693
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ALG5 Antibody
Antibody SKU:CAB17693
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 34-190 of human ALG5 (NP_037470.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, HepG2, 293T
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 34-190 of human ALG5 (NP_037470.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPAL HRHE EEKF FLNA KGQK ETLP SIWD SPTK QLSV VVPS YNEE KRLP VMMD EALS YLEK RQKR DPAF TYEV IVVD DGSK DQTS KVAF KYCQ KYGS DKVR VITL VKNR GKGG AIRM GIFS SRGE KILM ADAD GATK FPDV EKLE KGLN DLQP WPNQ M
Gene ID:29880
Uniprot:Q9Y673
Cellular Location:
Calculated MW:33kDa/36kDa
Observed MW:37kDa
Anti-ALG5 Antibody (CAB17693)Western blot - ALG5 Rabbit pAb (CAB17693)
Synonyms:ALG5, bA421P11.2
Background:This gene encodes a member of the glycosyltransferase 2 family. The encoded protein participates in glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
UniProt Protein Function:ALG5: a member of the glycosyltransferase 2 family. The encoded protein participates in glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
UniProt Protein Details:

Protein type:Membrane protein, integral; Transferase; EC 2.4.1.117; Glycan Metabolism - N-glycan biosynthesis

Chromosomal Location of Human Ortholog: 13q13.3

Cellular Component: endoplasmic reticulum membrane; membrane

Molecular Function:dolichyl-phosphate beta-D-mannosyltransferase activity; dolichyl-phosphate beta-glucosyltransferase activity; dolichyl-phosphate-mannose-protein mannosyltransferase activity; oligosaccharyl transferase activity

Biological Process: dolichol metabolic process; GPI anchor biosynthetic process; protein amino acid glycosylation; protein amino acid N-linked glycosylation; protein amino acid N-linked glycosylation via asparagine; protein amino acid O-linked mannosylation

NCBI Summary:This gene encodes a member of the glycosyltransferase 2 family. The encoded protein participates in glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
UniProt Code:Q9Y673
NCBI GenInfo Identifier:27734217
NCBI Gene ID:29880
NCBI Accession:Q9Y673.1
UniProt Secondary Accession:Q9Y673,Q5TBA6, B4DR37,
UniProt Related Accession:Q9Y673
Molecular Weight:33,525 Da
NCBI Full Name:Dolichyl-phosphate beta-glucosyltransferase
NCBI Synonym Full Names:ALG5, dolichyl-phosphate beta-glucosyltransferase
NCBI Official Symbol:ALG5  
NCBI Official Synonym Symbols:bA421P11.2  
NCBI Protein Information:dolichyl-phosphate beta-glucosyltransferase
UniProt Protein Name:Dolichyl-phosphate beta-glucosyltransferase
UniProt Synonym Protein Names:Asparagine-linked glycosylation protein 5 homolog
Protein Family:Dolichyl-phosphate beta-glucosyltransferase
UniProt Gene Name:ALG5  
UniProt Entry Name:ALG5_HUMAN
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