Cell Biology Antibodies 14

Anti-ALG13 Antibody (CAB18115)

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SKU:
CAB18115
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ALG13 Antibody
Antibody SKU:CAB18115
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant protein of human ALG13.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:Raji, K-562, Jurkat, HepG2, Mouse liver, Mouse kidney
Immunogen:Recombinant protein of human ALG13.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:79868
Uniprot:Q9NP73
Cellular Location:
Calculated MW:18kDa/106kDa/117kDa/126kDa
Observed MW:126kDa
Anti-ALG13 Antibody (CAB18115)Western blot - ALG13 Rabbit pAb (CAB18115)
Synonyms:CDG1S, CXorf45, EIEE36, GLT28D1, MDS031, TDRD13, YGL047W, ALG13
Background:The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:ALG13: Isoform 2 may be involved in protein N-glycosylation, second step of the dolichol-linked oligosaccharide pathway. Belongs to the glycosyltransferase 28 family. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:EC 3.4.19.12; Transferase; EC 2.4.1.141; Glycan Metabolism - N-glycan biosynthesis

Chromosomal Location of Human Ortholog: Xq23

Cellular Component: endoplasmic reticulum membrane

Molecular Function:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity

Biological Process: dolichol-linked oligosaccharide biosynthetic process

Disease: Congenital Disorder Of Glycosylation, Type Is

NCBI Summary:The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase. It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
UniProt Code:Q9NP73
NCBI GenInfo Identifier:298286785
NCBI Gene ID:79868
NCBI Accession:Q9NP73.2
UniProt Secondary Accession:Q9NP73,Q17RC3, Q5JXY9, B1AKD6, B1AKM1, B2R5L5, B7Z6J0 B7Z804, B7Z847, B7Z9A8, B7ZAJ1, B7ZB57,
UniProt Related Accession:Q9NP73
Molecular Weight:106,858 Da
NCBI Full Name:Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13
NCBI Synonym Full Names:ALG13, UDP-N-acetylglucosaminyltransferase subunit
NCBI Official Symbol:ALG13  
NCBI Official Synonym Symbols:CDG1S; EIEE36; MDS031; TDRD13; CXorf45; GLT28D1; YGL047W  
NCBI Protein Information:putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13
UniProt Protein Name:Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13
UniProt Synonym Protein Names:Asparagine-linked glycosylation 13 homolog; Glycosyltransferase 28 domain-containing protein 1; UDP-N-acetylglucosamine transferase subunit ALG13 homolog
Protein Family:UDP-N-acetylglucosamine transferase
UniProt Gene Name:ALG13  
UniProt Entry Name:ALG13_HUMAN
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