Name: Anti-ALDH9A1 Antibody (CAB7875)
Brand: Cell Biology Antibodies 11
SKU: CAB7875
Availability: OutOfStock

Antibody Name:	Anti-ALDH9A1 Antibody
Antibody SKU:	CAB7875
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthetic peptide of human ALDH9A1

Application:	WB IHC IF
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	HeLa, 22Rv1, NCI-H460, Mouse liver, Mouse kidney, Rat liver, Rat kidney

Immunogen:	A synthetic peptide of human ALDH9A1
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	223
Uniprot:	P49189
Cellular Location:	Cytoplasm
Calculated MW:	46kDa/53kDa
Observed MW:	54kDa

Synonyms:	ALDH9A1, ALDH4, ALDH7, ALDH9, E3, TMABADH
Background:	This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits.

UniProt Protein Function:	ALDH9A1: Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Belongs to the aldehyde dehydrogenase family.
UniProt Protein Details:	Protein type:Other Amino Acids Metabolism - beta-alanine; Lipid Metabolism - fatty acid; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - ascorbate and aldarate; Oxidoreductase; Amino Acid Metabolism - tryptophan; EC 1.2.1.47; EC 1.2.1.3; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - butanoate; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - propanoate; Mitochondrial; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pyruvate Chromosomal Location of Human Ortholog: 1q23.1 Cellular Component: cytoplasm; cytosol Molecular Function:3-chloroallyl aldehyde dehydrogenase activity; 4-trimethylammoniobutyraldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aminobutyraldehyde dehydrogenase activity Biological Process: aldehyde metabolic process; carnitine biosynthetic process; hormone metabolic process; neurotransmitter biosynthetic process
NCBI Summary:	This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]
UniProt Code:	P49189
NCBI GenInfo Identifier:	62511242
NCBI Gene ID:	223
NCBI Accession:	P49189.3
UniProt Secondary Accession:	P49189,Q5VV90, Q6LCL1, Q9NZT7, B2R6X1, B4DXY7,
UniProt Related Accession:	P49189
Molecular Weight:	46,455 Da
NCBI Full Name:	4-trimethylaminobutyraldehyde dehydrogenase
NCBI Synonym Full Names:	aldehyde dehydrogenase 9 family member A1
NCBI Official Symbol:	ALDH9A1
NCBI Official Synonym Symbols:	E3; ALDH4; ALDH7; ALDH9; TMABADH
NCBI Protein Information:	4-trimethylaminobutyraldehyde dehydrogenase
UniProt Protein Name:	4-trimethylaminobutyraldehyde dehydrogenase
UniProt Synonym Protein Names:	Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1 (EC:1.2.1.3); Gamma-aminobutyraldehyde dehydrogenase (EC:1.2.1.19); R-aminobutyraldehyde dehydrogenase
Protein Family:	Aldehyde dehydrogenase family
UniProt Gene Name:	ALDH9A1
UniProt Entry Name:	AL9A1_HUMAN

	Western blot analysis of extracts of various cell lines, using ALDH9A1 antibody (CAB7875) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
	Immunohistochemistry of paraffin-embedded rat heart using ALDH9A1 antibody (CAB7875) (40x lens).