Anti-ALDH7A1 Antibody (CAB20888)
- SKU:
- CAB20888
Description
| Antibody Name: | Anti-ALDH7A1 Antibody (CAB20888) |
| Antibody SKU: | CAB20888 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of Human ALDH7A1. |
| Application: | Western blotting |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, HepG2, SH-SY5Y, Mouse liver, Mouse kidney |
| Immunogen: | Recombinant protein of Human ALDH7A1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Cellular Location: | Cytoplasm, Mitochondrion, Nucleus, cytosol |
| Calculated MW: | 51kDa/55kDa/58kDa |
| Observed MW: | 58KDa |
| Synonyms: | ALDH7A1, ATQ1, EPD, PDE |
| Background: | The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. |
 | Western blot analysis of extracts of various cell lines, using ALDH7A1 antibody at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s. |
Additional Information
Product Type: |
Antibody |
Antibody Type: |
Polyclonal Antibody |
Reactivity: |
Plant |
Host Species: |
Rabbit |
Isotype: |
IgG |
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