Metabolism Antibodies 3
Anti-ALDH1L1 Antibody (CAB7707)
(No reviews yet)
Write a Review
- SKU:
- CAB7707
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-ALDH1L1 Antibody |
| Antibody SKU: | CAB7707 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human ALDH1L1 |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse liver, Rat liver |
| Immunogen: | A synthesized peptide derived from human ALDH1L1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10840 |
| Uniprot: | O75891 |
| Cellular Location: | |
| Calculated MW: | 99kDa |
| Observed MW: | 100KDa |
| Synonyms: | 10-FTHFDH, 10-fTHF, FDH, FTHFD |
| Background: | The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
| UniProt Protein Function: | ALDH1L1: 2 isoforms of the human protein are produced by alternative splicing |
| UniProt Protein Details: | Protein type:Cofactor and Vitamin Metabolism - one carbon pool by folate; Oxidoreductase; EC 1.5.1.6 Chromosomal Location of Human Ortholog: 3q21.3 Cellular Component: mitochondrion Molecular Function:methyltransferase activity; aldehyde dehydrogenase (NAD) activity; formyltetrahydrofolate dehydrogenase activity; hydroxymethyl-, formyl- and related transferase activity; catalytic activity Biological Process: methylation; biosynthetic process; one-carbon compound metabolic process; 10-formyltetrahydrofolate catabolic process |
| NCBI Summary: | The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
| UniProt Code: | O75891 |
| NCBI GenInfo Identifier: | 59802911 |
| NCBI Gene ID: | 10840 |
| NCBI Accession: | O75891.2 |
| UniProt Secondary Accession: | O75891,Q68CS1, B4DG36, E9PBX3, |
| UniProt Related Accession: | O75891 |
| Molecular Weight: | 902 |
| NCBI Full Name: | Cytosolic 10-formyltetrahydrofolate dehydrogenase |
| NCBI Synonym Full Names: | aldehyde dehydrogenase 1 family, member L1 |
| NCBI Official Symbol: | ALDH1L1 |
| NCBI Official Synonym Symbols: | FDH; FTHFD; 10-fTHF; 10-FTHFDH |
| NCBI Protein Information: | cytosolic 10-formyltetrahydrofolate dehydrogenase; MER57B-ALDH1L1 |
| UniProt Protein Name: | Cytosolic 10-formyltetrahydrofolate dehydrogenase |
| UniProt Synonym Protein Names: | Aldehyde dehydrogenase family 1 member L1 |
| Protein Family: | Cytosolic 10-formyltetrahydrofolate dehydrogenase |
| UniProt Gene Name: | ALDH1L1 |
| UniProt Entry Name: | AL1L1_HUMAN |
 | Western blot - ALDH1L1 Rabbit mAb (CAB7707) |
View AllClose
Related Products
Anti-RANBP3 Antibody (CAB0092)
OverviewProduct Name:RANBP3 Rabbit mAbProduct Code:CAB0092Size:20uL, 50uL, 100uLSynonyms:RANBP3, ran-binding protein 3
Anti-QK1 Antibody (CAB0193)
OverviewProduct Name:QK1 Rabbit mAbProduct Code:CAB0193Size:20uL, 50uL, 100uLSynonyms:QKI, Hqk, QK, QK1, QK3, hqkI, protein quaking
Anti-DEK Antibody (CAB0315)
OverviewProduct Name:DEK Rabbit mAbProduct Code:CAB0315Size:20uL, 50uL, 100uLSynonyms:D6S231EApplications:WB,
Anti-EXOSC7 Antibody (CAB0501)
OverviewProduct Name:EXOSC7 Rabbit mAbProduct Code:CAB0501Size:20uL, 50uL, 100uLSynonyms:EXOSC7, EAP1, RRP42, Rrp42p, hRrp42p, p8, exoso