Cell Biology Antibodies 1

Anti-Albumin Antibody (CAB0353)

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SKU:
CAB0353
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-Albumin Antibody
Antibody SKU:CAB0353
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-255 of human Albumin (NP_000468.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:NCI-H460, MCF7, Mouse liver, Mouse blood
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-255 of human Albumin (NP_000468.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GVFR RDAH KSEV AHRF KDLG EENF KALV LIAF AQYL QQCP FEDH VKLV NEVT EFAK TCVA DESA ENCD KSLH TLFG DKLC TVAT LRET YGEM ADCC AKQE PERN ECFL QHKD DNPN LPRL VRPE VDVM CTAF HDNE ETFL KKYL YEIA RRHP YFYA PELL FFAK RYKA AFTE CCQA ADKA ACLL PKLD ELRD EGKA SSAK QRLK CASL QKFG ERAF KAWA VARL SQRF PKAE FAEV
Gene ID:213
Uniprot:P02768
Cellular Location:Secreted
Calculated MW:45kDa/47kDa/69kDa
Observed MW:69kDa
Synonyms:ALB, HSA, PRO0883, PRO0903, PRO1341, albumin, Albumin
Background:Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65, 000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.
UniProt Protein Function:albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted; Carrier; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; protein complex; extracellular region; basement membrane; nucleus

Molecular Function:antioxidant activity; toxin binding; protein binding; copper ion binding; enzyme binding; DNA binding; zinc ion binding; chaperone binding; drug binding; oxygen binding; fatty acid binding; pyridoxal phosphate binding

Biological Process: receptor-mediated endocytosis; platelet activation; sodium-independent organic anion transport; maintenance of mitochondrion localization; bile acid metabolic process; lipoprotein metabolic process; hemolysis by symbiont of host red blood cells; cellular response to starvation; response to mercury ion; bile acid and bile salt transport; response to organic substance; retinal homeostasis; platelet degranulation; transport; negative regulation of programmed cell death; blood coagulation; transmembrane transport; positive regulation of circadian sleep/wake cycle, non-REM sleep; response to nutrient; negative regulation of apoptosis

Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic

NCBI Summary:Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008]
UniProt Code:P02768
NCBI GenInfo Identifier:113576
NCBI Gene ID:213
NCBI Accession:P02768.2
UniProt Secondary Accession:P02768,O95574, P04277, Q13140, Q645G4, Q68DN5, Q6UXK4 Q86YG0, Q9P157, Q9P1I7, Q9UHS3, Q9UJZ0,
UniProt Related Accession:P02768
Molecular Weight:Predicted: 67 kDaObserved: 57, 67 kDa
NCBI Full Name:Serum albumin
NCBI Synonym Full Names:albumin
NCBI Official Symbol:ALB  
NCBI Official Synonym Symbols:FDAH; ANALBA; PRO0883; PRO0903; PRO1341  
NCBI Protein Information:serum albumin; albumin (32 AA); albumin (AA 34); growth-inhibiting protein 20; cell growth inhibiting protein 42
UniProt Protein Name:Serum albumin
Protein Family:Albumin
UniProt Gene Name:ALB  
UniProt Entry Name:ALBU_HUMAN
Anti-Albumin Antibody (CAB0353)Western blot analysis of extracts of various cell lines, using Albumin antibody (CAB0353) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s.
Anti-Albumin Antibody (CAB0353)Immunohistochemistry of paraffin-embedded rat brain using Albumin antibody (CAB0353) at dilution of 1:100 (40x lens).
Anti-Albumin Antibody (CAB0353)Immunohistochemistry of paraffin-embedded mouse brain using Albumin antibody (CAB0353) at dilution of 1:100 (40x lens).
Anti-Albumin Antibody (CAB0353)Immunofluorescence analysis of rat liver using Albumin antibody (CAB0353) at dilution of 1:100. Blue: DAPI for nuclear staining.
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