Cell Biology Antibodies 4

Anti-AKR1E2 Antibody (CAB13730)

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SKU:
CAB13730
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-AKR1E2 Antibody
Antibody SKU:CAB13730
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human AKR1E2 (NP_001035267.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human AKR1E2 (NP_001035267.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGDI PAVG LSSW KASP GKVT EAVK EAID AGYR HFDC AYFY HNER EVGA GIRC KIKE GAVR REDL FIAT KLWC TCHK KSLV ETAC RKSL KALK LNYL DLYL IHWP MGFK PPHP EWIM SCSE LSFC LSHP RVQD LPLD ESNM VIPS DTDF LD
Gene ID:83592
Uniprot:Q96JD6
Cellular Location:Cytoplasm
Calculated MW:25kDa/28kDa/30kDa/34kDa/36kDa
Observed MW:Refer to figures
Synonyms:AKR1E2, AKR1CL2, AKRDC1, LoopADR, hTSP, htAKR, TAKR, 1
Background:The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:AKR1CL2: Catalyzes the NADPH-dependent reduction of 1,5-anhydro- D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones. Has low NADPH-dependent reductase activity towards 9,10- phenanthrenequinone (in vitro). Belongs to the aldo/keto reductase family. 5 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Oxidoreductase; EC 1.1.1.263

Chromosomal Location of Human Ortholog: 10p15.1

NCBI Summary:The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
UniProt Code:Q96JD6
NCBI GenInfo Identifier:269849539
NCBI Gene ID:83592
NCBI Accession:Q96JD6.2
UniProt Secondary Accession:Q96JD6,Q86Z16, Q86Z17, Q86Z18, Q9BU71,
UniProt Related Accession:Q96JD6
Molecular Weight:25,693 Da
NCBI Full Name:1,5-anhydro-D-fructose reductase
NCBI Synonym Full Names:aldo-keto reductase family 1 member E2
NCBI Official Symbol:AKR1E2  
NCBI Official Synonym Symbols:hTSP; htAKR; AKRDC1; AKR1CL2; LoopADR  
NCBI Protein Information:1,5-anhydro-D-fructose reductase
UniProt Protein Name:1,5-anhydro-D-fructose reductase
UniProt Synonym Protein Names:Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member E2; LoopADR; Testis-specific protein; hTSP
Protein Family:1,5-anhydro-D-fructose reductase
UniProt Gene Name:AKR1E2  
UniProt Entry Name:AKCL2_HUMAN
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