Metabolism Antibodies 1

Anti-AGPAT5 Antibody (CAB12884)

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SKU:
CAB12884
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-AGPAT5 Antibody
Antibody SKU:CAB12884
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 120-320 of human AGPAT5 (NP_060831.2).
Application:WB
Recommended Dilution:WB 1:1000 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 120-320 of human AGPAT5 (NP_060831.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KEGL KWLP LYGC YFAQ HGGI YVKR SAKF NEKE MRNK LQSY VDAG TPMY LVIF PEGT RYNP EQTK VLSA SQAF AAQR GLAV LKHV LTPR IKAT HVAF DCMK NYLD AIYD VTVV YEGK DDGG QRRE SPTM TEFL CKEC PKIH IHID RIDK KDVP EEQE HMRR WLHE RFEI KDKM LIEF YESP DPER RKRF PGKS VNSK LSIK K
Gene ID:55326
Uniprot:Q9NUQ2
Cellular Location:Endoplasmic reticulum membrane, Mitochondrion, Multi-pass membrane protein, Nucleus envelope
Calculated MW:42kDa
Observed MW:Refer to Figures
Synonyms:AGPAT5, 1AGPAT5, LPAATE
Background:This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. A pseudogene of this gene is present on the Y chromosome.
UniProt Protein Function:AGPAT5: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
UniProt Protein Details:

Protein type:Transferase; EC 2.3.1.51; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: endoplasmic reticulum membrane; mitochondrial outer membrane; mitochondrion

Molecular Function:1-acylglycerol-3-phosphate O-acyltransferase activity; protein binding

Biological Process: phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process

NCBI Summary:This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. A pseudogene of this gene is present on the Y chromosome. [provided by RefSeq, Aug 2014]
UniProt Code:Q9NUQ2
NCBI GenInfo Identifier:30923427
NCBI Gene ID:55326
NCBI Accession:Q9NUQ2.3
UniProt Secondary Accession:Q9NUQ2,Q8IZ47, Q9BQG4,
UniProt Related Accession:Q9NUQ2
Molecular Weight:42,072 Da
NCBI Full Name:1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
NCBI Synonym Full Names:1-acylglycerol-3-phosphate O-acyltransferase 5
NCBI Official Symbol:AGPAT5  
NCBI Official Synonym Symbols:LPAATE; 1AGPAT5  
NCBI Protein Information:1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
UniProt Protein Name:1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon
UniProt Synonym Protein Names:1-acylglycerol-3-phosphate O-acyltransferase 5; 1-AGP acyltransferase 5; 1-AGPAT 5; Lysophosphatidic acid acyltransferase epsilon; LPAAT-epsilon
Protein Family:1-acyl-sn-glycerol-3-phosphate acyltransferase
UniProt Gene Name:AGPAT5  
UniProt Entry Name:PLCE_HUMAN
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