Metabolism Antibodies 1

Anti-AFMID Antibody (CAB14441)

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SKU:
CAB14441
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-AFMID Antibody
Antibody SKU:CAB14441
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human AFMID (NP_001010982.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:A-431, Mouse kidney, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human AFMID (NP_001010982.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MMDV SGVG FPSK VPWK KMSA EELE NQYC PSRW VVRL GAEE ALRT YSQI GIEA TTRA RATR KSLL HVPY GDGE GEKV DIYF PDES SEAL PFFL FFHG GYWQ SGSK DESA FMVH PLTA QGVA VVIV AYGI APKG TLDH MVDQ VTRS VAFV QKRY PSNK GIYL CGHS AGAH LAAM MLLA DWTK HGVT PNLR GFFL VSGV FDLE PIVY TSQN VALQ LTLE DAQR NSPQ LKVA QAQP VDPT CRVL VVVG QFDS PEFH RQSW EFYQ TLCQ GEWK ASFE ELHD VDHF EIVE NLTQ KDNV LTQI ILKT IFQ
Gene ID:125061
Uniprot:Q63HM1
Cellular Location:Cytoplasm, Nucleus, cytosol
Calculated MW:33kDa/34kDa
Observed MW:34kDa
Synonyms:AFMID, FKF, KF, KFA
Background:
UniProt Protein Function:AFMID: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. Belongs to the kynurenine formamidase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Hydrolase; Amino Acid Metabolism - tryptophan; EC 3.5.1.9; Carbohydrate Metabolism - glyoxylate and dicarboxylate

Chromosomal Location of Human Ortholog: 17q25.3

UniProt Code:Q63HM1
NCBI GenInfo Identifier:259016175
NCBI Gene ID:125061
NCBI Accession:Q63HM1.2
UniProt Secondary Accession:Q63HM1,A2RUB3,
UniProt Related Accession:Q63HM1
Molecular Weight:34,528 Da
NCBI Full Name:Kynurenine formamidase
NCBI Synonym Full Names:arylformamidase
NCBI Official Symbol:AFMID  
NCBI Official Synonym Symbols:KF; FKF; KFA  
NCBI Protein Information:kynurenine formamidase
UniProt Protein Name:Kynurenine formamidase
UniProt Synonym Protein Names:Arylformamidase
UniProt Gene Name:AFMID  
UniProt Entry Name:KFA_HUMAN
Anti-AFMID Antibody (CAB14441)Western blot analysis of extracts of various cell lines, using AFMID antibody (CAB14441) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 15s.
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