Cell Biology Antibodies 6
Anti-AFAP1L2 Antibody (CAB15916)
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- SKU:
- CAB15916
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-AFAP1L2 Antibody |
| Antibody SKU: | CAB15916 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AFAP1L2 (NP_001001936.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-87MG, LO2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AFAP1L2 (NP_001001936.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MERY KALE QLLT ELDD FLKI LDQE NLSS TALV KKSC LAEL LRLY TKSS SSDE EYIY MNKV TINK QQNA ESQG KAPE EQGL LPNG EPSQ HSSA PQKS LPDL PPPK MIPE RKQL AIPK TESP EGYY EEAE PYDT SLNE DGEA VSSS YESY DEED GSKG KSAP YQWP SPEA GIEL MRDA RICA FLWR KKWL GQWA KQLC VIKD NRLL CYKS SKDH SPQL DVNL LGSS VIHK EKQV RKKE HKLK ITPM NADV IVLG LQSK DQAE QWLR VIQE VSGL PSEG ASEG NQYT PDAQ RFNC QKPD IAEK |
| Gene ID: | 84632 |
| Uniprot: | Q8N4X5 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 38kDa/90kDa/91kDa/93kDa |
| Observed MW: | 110kDa |
| Synonyms: | AFAP1L2, CTB-1144G6.4, KIAA1914, XB130 |
| Background: |
| UniProt Protein Function: | AFAP1L2: May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Activator Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: cytoplasm; plasma membrane Molecular Function:protein tyrosine kinase activator activity; SH2 domain binding; SH3 domain binding Biological Process: positive regulation of interleukin-8 production; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of transcription, DNA-dependent; regulation of mitotic cell cycle; regulation of interleukin-6 production; inflammatory response |
| UniProt Code: | Q8N4X5 |
| NCBI GenInfo Identifier: | 68052360 |
| NCBI Gene ID: | 84632 |
| NCBI Accession: | Q8N4X5.1 |
| UniProt Secondary Accession: | Q8N4X5,Q2UZW3, Q8TB54, Q96PX4, Q96SY5, A8K6P7, B3KVQ8 |
| UniProt Related Accession: | Q8N4X5 |
| Molecular Weight: | 93,894 Da |
| NCBI Full Name: | Actin filament-associated protein 1-like 2 |
| NCBI Synonym Full Names: | actin filament associated protein 1-like 2 |
| NCBI Official Symbol: | AFAP1L2 |
| NCBI Official Synonym Symbols: | XB130; KIAA1914; CTB-1144G6.4 |
| NCBI Protein Information: | actin filament-associated protein 1-like 2; AFAP1-like protein 2 |
| UniProt Protein Name: | Actin filament-associated protein 1-like 2 |
| Protein Family: | Actin filament-associated protein |
| UniProt Gene Name: | AFAP1L2 |
| UniProt Entry Name: | AF1L2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using AFAP1L2 antibody (CAB15916) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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