Cell Biology Antibodies 15
Anti-ADORA3 Antibody (CAB18524)
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- SKU:
- CAB18524
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ADORA3 Antibody |
| Antibody SKU: | CAB18524 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ADORA3. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant protein of human ADORA3. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 140 |
| Uniprot: | P0DMS8 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | A3AR, ADORA3 |
| Background: |
| UniProt Protein Function: | ADORA3: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Possible role in reproduction. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p13.2 Cellular Component: plasma membrane |
| NCBI Summary: | This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Alternative splicing results in multiple transcript variants. This gene shares its 5' terminal exon with some transcripts from overlapping GeneID:57413, which encodes an immunoglobulin domain-containing protein. [provided by RefSeq, Nov 2014] |
| UniProt Code: | P0DMS8 |
| NCBI GenInfo Identifier: | 803374855 |
| NCBI Gene ID: | 140 |
| NCBI Accession: | P0DMS8.1 |
| UniProt Secondary Accession: | P0DMS8,P33765, Q6UWU0, Q9BYZ1, A2A3P4, |
| UniProt Related Accession: | P0DMS8 |
| Molecular Weight: | 38,976 Da |
| NCBI Full Name: | Adenosine receptor A3 |
| NCBI Synonym Full Names: | adenosine A3 receptor |
| NCBI Official Symbol: | ADORA3 |
| NCBI Official Synonym Symbols: | A3AR |
| NCBI Protein Information: | adenosine receptor A3 |
| UniProt Protein Name: | Adenosine receptor A3 |
| Protein Family: | Adenosine receptor |
| UniProt Gene Name: | ADORA3 |
| UniProt Entry Name: | AA3R_HUMAN |
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