Cell Biology Antibodies 5

Anti-ADH1A Antibody (CAB14701)

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SKU:
CAB14701
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ADH1A Antibody
Antibody SKU:CAB14701
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human ADH1A (NP_000658.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:LO2, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 220-300 of human ADH1A (NP_000658.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:IIAV DINK DKFA KAKE LGAT ECIN PQDY KKPI QEVL KEMT DGGV DFSF EVIG RLDT MMAS LLCC HEAC GTSV IVGV PPDS Q
Gene ID:124
Uniprot:P07327
Cellular Location:Cytoplasm
Calculated MW:39kDa
Observed MW:40kDa
Synonyms:ADH1A, ADH1
Background:This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.
UniProt Code:P07327
NCBI GenInfo Identifier:4501929
NCBI Gene ID:124
NCBI Accession:NP_000658.1
UniProt Secondary Accession:P07327,Q17R68, A8K3E3,
UniProt Related Accession:P07327
Molecular Weight:375
NCBI Full Name:alcohol dehydrogenase 1A
NCBI Synonym Full Names:alcohol dehydrogenase 1A (class I), alpha polypeptide
NCBI Official Symbol:ADH1A  
NCBI Official Synonym Symbols:ADH1  
NCBI Protein Information:alcohol dehydrogenase 1A; ADH, alpha subunit; aldehyde reductase; alcohol dehydrogenase subunit alpha; alcohol dehydrogenase 1 (class I), alpha polypeptide
UniProt Protein Name:Alcohol dehydrogenase 1A
UniProt Synonym Protein Names:Alcohol dehydrogenase subunit alpha
Protein Family:Alcohol dehydrogenase
UniProt Gene Name:ADH1A  
UniProt Entry Name:ADH1A_HUMAN
Anti-ADH1A Antibody (CAB14701)Western blot analysis of extracts of various cell lines, using ADH1A antibody (CAB14701) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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