Cell Biology Antibodies 3

Anti-ADGRD1 Antibody (CAB12629)

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SKU:
CAB12629
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ADGRD1 Antibody
Antibody SKU:CAB12629
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 805-874 of human ADGRD1 (NP_942122.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, LO2, 293T, Mouse kidney, Mouse liver, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 805-874 of human ADGRD1 (NP_942122.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FHCL LNSE VRAA FKHK TKVW SLTS SSAR TSNA KPFH SDLM NGTR PGMA STKL SPWD KSSH SAHR VDLS AV
Gene ID:283383
Uniprot:Q6QNK2
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:43kDa/61kDa/96kDa/99kDa
Observed MW:105kDa
Synonyms:ADGRD1, GPR133, PGR25
Background:
UniProt Protein Function:GPR133: Orphan receptor. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 12q24.33

Cellular Component: plasma membrane

Molecular Function:G-protein coupled receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway

NCBI Summary:The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins (summary by Bjarnadottir et al., 2004 [PubMed 15203201]).[supplied by OMIM, Nov 2010]
UniProt Code:Q6QNK2
NCBI GenInfo Identifier:59797935
NCBI Gene ID:283383
NCBI Accession:Q6QNK2.1
UniProt Secondary Accession:Q6QNK2,Q2M1L3, Q6ZMQ1, Q7Z7M2, Q86SM4, B2CKK9, B7ZLF7
UniProt Related Accession:Q6QNK2
Molecular Weight:99,984 Da
NCBI Full Name:Adhesion G-protein coupled receptor D1
NCBI Synonym Full Names:adhesion G protein-coupled receptor D1
NCBI Official Symbol:ADGRD1  
NCBI Official Synonym Symbols:PGR25; GPR133  
NCBI Protein Information:adhesion G-protein coupled receptor D1
UniProt Protein Name:Adhesion G-protein coupled receptor D1
UniProt Synonym Protein Names:G-protein coupled receptor 133; G-protein coupled receptor PGR25
UniProt Gene Name:ADGRD1  
UniProt Entry Name:AGRD1_HUMAN
Anti-ADGRD1 Antibody (CAB12629)Western blot analysis of extracts of various cell lines, using ADGRD1 antibody (CAB12629) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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