Signal Transduction Antibodies 2

Anti-ADGRA3 Antibody (CAB15573)

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SKU:
CAB15573
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-ADGRA3 Antibody
Antibody SKU:CAB15573
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 370-600 of human ADGRA3 (NP_660333.2).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 370-600 of human ADGRA3 (NP_660333.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:ITAY LQCT RNTH GSGI YPGN PQDE RKAW RRCD RGGF WADD DYSR CQYA NDVT RVLY MFNQ MPLN LTNA VATA RQLL AYTV EAAN FSDK MDVI FVAE MIEK FGRF TKEE KSKE LGDV MVDI ASNI MLAD ERVL WLAQ REAK ACSR IVQC LQRI ATYR LAGG AHVY STYS PNIA LEAY VIKS TGFT GMTC TVFQ KVAA SDRT GLSD YGRR DPEG NLDK QLSF KCNV SNTF SSL
Gene ID:166647
Uniprot:Q8IWK6
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:42kDa/68kDa/131kDa/146kDa
Observed MW:146kDa
Synonyms:ADGRA3, GPR125, PGR21, TEM5L
Background:This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia.
UniProt Protein Function:GPR125: Orphan receptor. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 4p15.2

Cellular Component: external side of plasma membrane; integral component of membrane

Molecular Function:G-protein coupled receptor activity

Biological Process: cell surface receptor signaling pathway; G-protein coupled receptor signaling pathway

NCBI Summary:This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila disc large tumor suppressor gene. This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia. [provided by RefSeq, Oct 2012]
UniProt Code:Q8IWK6
NCBI GenInfo Identifier:59823631
NCBI Gene ID:166647
NCBI Accession:NP_660333.2
UniProt Related Accession:Q8IWK6
Molecular Weight:
NCBI Full Name:adhesion G protein-coupled receptor A3
NCBI Synonym Full Names:adhesion G protein-coupled receptor A3
NCBI Official Symbol:ADGRA3  
NCBI Official Synonym Symbols:PGR21; TEM5L; GPR125  
NCBI Protein Information:adhesion G protein-coupled receptor A3
UniProt Protein Name:Adhesion G protein-coupled receptor A3
UniProt Synonym Protein Names:G-protein coupled receptor 125
UniProt Gene Name:ADGRA3  
Anti-ADGRA3 Antibody (CAB15573)Western blot analysis of extracts of Mouse liver, using ADGRA3 Rabbit pAb (CAB15573) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min.
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