Cell Biology Antibodies 14

Anti-ADCY9 Antibody (CAB16795)

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SKU:
CAB16795
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ADCY9 Antibody
Antibody SKU:CAB16795
Antibody Size:20uL, 50 uL
Application:WB
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 550-780 of human ADCY9 (NP_001107.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 550-780 of human ADCY9 (NP_001107.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:VIER LGQS VVAD QLKG LKTY LISG QRAK ESRC SCAE ALLS GFEV IDGS QVSS GPRG QGTA SSGN VSDL AQTV KTFD NLKT CPSC GITF APKS EAGA EGGA PQNG CQDE HKNS TKAS GGPN PKTQ NGLL SPPQ EEKL TNSQ TSLC EILQ EKGR WAGV SLDQ SALL PLRF KNIR EKTD AHFV DVIK EDSL MKDY FFKP PINQ FSLN FLDQ ELER SYRT SYQE EVIK NSPV KTF
Gene ID:115
Uniprot:O60503
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:AC9, ACIX, ADCY9
Background:Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]
UniProt Protein Function:ADCY9: May play a fundamental role in situations where fine interplay between intracellular calcium and cAMP determines the cellular function. May be a physiologically relevant docking site for calcineurin. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Nucleotide Metabolism - purine; Membrane protein, integral; Lyase; Transporter, aquaporin family; EC 4.6.1.1; Adenylyl cyclase; Transporter

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane

Molecular Function:adenylate cyclase activity

Biological Process: activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cAMP-mediated signaling; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; renal water homeostasis; signal transduction

NCBI Summary:Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]
UniProt Code:O60503
NCBI GenInfo Identifier:27151764
NCBI Gene ID:115
NCBI Accession:O60503.4
UniProt Secondary Accession:O60503,O60273, Q4ZHT9, Q4ZIR5, Q9BWT4, Q9UGP2, A7E2V5 A7E2X2, D3DUD1,
UniProt Related Accession:O60503
Molecular Weight:150,701 Da
NCBI Full Name:Adenylate cyclase type 9
NCBI Synonym Full Names:adenylate cyclase 9
NCBI Official Symbol:ADCY9  
NCBI Official Synonym Symbols:AC9; ACIX  
NCBI Protein Information:adenylate cyclase type 9
UniProt Protein Name:Adenylate cyclase type 9
UniProt Synonym Protein Names:ATP pyrophosphate-lyase 9; Adenylate cyclase type IX
Protein Family:Adenylate cyclase
UniProt Gene Name:ADCY9  
UniProt Entry Name:ADCY9_HUMAN
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