Cell Biology Antibodies 6

Anti-ADAMDEC1 Antibody (CAB15435)

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SKU:
CAB15435
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-ADAMDEC1 Antibody
Antibody SKU:CAB15435
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 206-470 of human ADAMDEC1 (NP_055294.1).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human
Positive Samples:HT-29, MCF7
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 206-470 of human ADAMDEC1 (NP_055294.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:KSPE KEDF LRAQ KYID LYLV LDNA FYKN YNEN LTLI RSFV FDVM NLLN VIYN TIDV QVAL VGME IWSD GDKI KVVP SAST TFDN FLRW HSSN LGKK IHDH AQLL SGIS FNNR RVGL AASN SLCS PSSV AVIE AKKK NNVA LVGV MSHE LGHV LGMP DVPF NTKC PSGS CVMN QYLS SKFP KDFS TSCR AHFE RYLL SQKP KCLL QAPI PTNI MTTP VCGN HLLE VGED CDCG SPKE CTNL CCEA LTCK LKPG TDCG GDAP NHTT E
Gene ID:27299
Uniprot:O15204
Cellular Location:Secreted
Calculated MW:43kDa/52kDa
Observed MW:42-50kDa
Synonyms:ADAMDEC1, M12.219, ADAM DEC1
Background:This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells.
UniProt Protein Function:ADAMDEC1: May play an important role in the control of the immune response and during pregnancy. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Protease; EC 3.4.24.-; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 8p21.2

NCBI Summary:This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during dendritic cells maturation. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008]
UniProt Code:O15204
NCBI GenInfo Identifier:56404433
NCBI Gene ID:27299
NCBI Accession:O15204.2
UniProt Secondary Accession:O15204,B7ZAK5,
UniProt Related Accession:O15204
Molecular Weight:43,557 Da
NCBI Full Name:ADAM DEC1
NCBI Synonym Full Names:ADAM like decysin 1
NCBI Official Symbol:ADAMDEC1  
NCBI Official Synonym Symbols:M12.219  
NCBI Protein Information:ADAM DEC1
UniProt Protein Name:ADAM DEC1
UniProt Synonym Protein Names:A disintegrin and metalloproteinase domain-like protein decysin-1; ADAM-like protein decysin-1
Protein Family:ADAM
UniProt Gene Name:ADAMDEC1  
UniProt Entry Name:ADEC1_HUMAN
Anti-ADAMDEC1 Antibody (CAB15435)Western blot analysis of extracts of various cell lines, using ADAMDEC1 antibody (CAB15435) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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