| UniProt Protein Function: | ADAM20: May be involved in sperm maturation and/or fertilization. Protein type: Motility/polarity/chemotaxis; EC 3.4.24.-; Membrane protein, integral; Protease Chromosomal Location of Human Ortholog: 14q24.1 Cellular Component: integral to membrane; plasma membrane Molecular Function: zinc ion binding; metallopeptidase activity; metalloendopeptidase activity Biological Process: binding of sperm to zona pellucida; single fertilization; proteolysis; multicellular organism reproduction |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene is testis-specific. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43506 |
| NCBI GenInfo Identifier: | 50845382 |
| NCBI Gene ID: | 8748 |
| NCBI Accession: | NP_003805.3 |
| UniProt Secondary Accession: | O43506,Q6GTZ1, Q9UKJ9 |
| UniProt Related Accession: | O43506 |
| Molecular Weight: | 81,603 Da |
| NCBI Full Name: | disintegrin and metalloproteinase domain-containing protein 20 preproprotein |
| NCBI Synonym Full Names: | ADAM metallopeptidase domain 20 |
| NCBI Official Symbol: | ADAM20 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | disintegrin and metalloproteinase domain-containing protein 20; ADAM 20; a disintegrin and metalloproteinase domain 20 |
| UniProt Protein Name: | Disintegrin and metalloproteinase domain-containing protein 20 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Disintegrin and metalloproteinase domain-containing protein |
| UniProt Gene Name: | ADAM20 |
| UniProt Entry Name: | ADA20_HUMAN |
