Anti-ADA2 Antibody (CAB20265)
- SKU:
- CAB20265
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- PAN
- Synonyms:
- ADGF
- Synonyms:
- CECR1
- Synonyms:
- IDGFL
- Synonyms:
- SNEDS
- Synonyms:
- VAIHS
Description
| Product Name: | ADA2 Rabbit pAb |
| Product Code: | CAB20265 |
| Size: | 50uL, 100uL |
| Synonyms: | PAN, ADGF, CECR1, IDGFL, SNEDS, VAIHS |
| Applications: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ADA2. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | Rat plasma |
| Immunogen: | Recombinant protein of human ADA2. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 51816 |
| Uniprot: | Q9NZK5 |
| Observed MW: | 59KDa |
| UniProt Protein Function: | CECR1: Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity. Belongs to the adenosine and AMP deaminases family. ADGF subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.5.4.4; Hydrolase; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 22q11.1 Cellular Component: cytosol; extracellular region; extracellular space Molecular Function:adenosine deaminase activity; adenosine receptor binding; growth factor activity; protein homodimerization activity; proteoglycan binding; zinc ion binding Biological Process: adenosine catabolic process; cellular protein metabolic process; hypoxanthine salvage; inosine biosynthetic process Disease: Polyarteritis Nodosa, Childhood-onset; Sneddon Syndrome |
| NCBI Summary: | This gene encodes a member of a subfamily of the adenosine deaminase protein family. The encoded protein is one of two adenosine deaminases found in humans, which regulate levels of the signaling molecule, adenosine. The encoded protein is secreted from monocytes undergoing differentiation and may regulate cell proliferation and differentiation. This gene may be responsible for some of the phenotypic features associated with cat eye syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
| UniProt Code: | Q9NZK5 |
| NCBI GenInfo Identifier: | 122065151 |
| NCBI Gene ID: | 51816 |
| NCBI Accession: | Q9NZK5.2 |
| UniProt Secondary Accession: | Q9NZK5,Q6ICF1, Q86UB6, Q8NCJ2, Q96K41, A8K9H4, |
| UniProt Related Accession: | Q9NZK5 |
| Molecular Weight: | 30,668 Da |
| NCBI Full Name: | Adenosine deaminase CECR1 |
| NCBI Synonym Full Names: | cat eye syndrome chromosome region, candidate 1 |
| NCBI Official Symbol: | CECR1 |
| NCBI Official Synonym Symbols: | PAN; ADA2; ADGF; IDGFL; SNEDS |
| NCBI Protein Information: | adenosine deaminase CECR1 |
| UniProt Protein Name: | Adenosine deaminase CECR1 |
| UniProt Synonym Protein Names: | Cat eye syndrome critical region protein 1 |
| Protein Family: | Adenosine deaminase |
| UniProt Gene Name: | CECR1 |
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