Signal Transduction Antibodies 2
Anti-ACYP2 Antibody (CAB15636)
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- SKU:
- CAB15636
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-ACYP2 Antibody |
| Antibody SKU: | CAB15636 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-99 of human ACYP2 (NP_612457.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, Mouse brain, Mouse heart, Mouse kidney, Rat skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-99 of human ACYP2 (NP_612457.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSTA QSLK SVDY EVFG RVQG VCFR MYTE DEAR KIGV VGWV KNTS KGTV TGQV QGPE DKVN SMKS WLSK VGSP SSRI DRTN FSNE KTIS KLEY SNFS IRY |
| Gene ID: | 98 |
| Uniprot: | P14621 |
| Cellular Location: | |
| Calculated MW: | 11kDa |
| Observed MW: | 11kDa |
| Synonyms: | ACYP2, ACYM, ACYP |
| Background: | Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. Several transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | ACYP2: Its physiological role is not yet clear. Belongs to the acylphosphatase family. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - pyruvate; EC 3.6.1.7; Hydrolase; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2p16.2 Cellular Component: mitochondrion Molecular Function:acylphosphatase activity Biological Process: phosphate metabolic process |
| NCBI Summary: | Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P14621 |
| NCBI GenInfo Identifier: | 2822108 |
| NCBI Gene ID: | 98 |
| NCBI Accession: | P14621.2 |
| UniProt Related Accession: | P14621 |
| Molecular Weight: | 11,140 Da |
| NCBI Full Name: | Acylphosphatase-2 |
| NCBI Synonym Full Names: | acylphosphatase 2, muscle type |
| NCBI Official Symbol: | ACYP2 |
| NCBI Official Synonym Symbols: | ACYM; ACYP |
| NCBI Protein Information: | acylphosphatase-2; acylphosphate phosphohydrolase 2; acylphosphatase, muscle type isozyme |
| UniProt Protein Name: | Acylphosphatase-2 |
| UniProt Synonym Protein Names: | Acylphosphatase, muscle type isozyme; Acylphosphate phosphohydrolase 2 |
| Protein Family: | Acylphosphatase |
| UniProt Gene Name: | ACYP2 |
| UniProt Entry Name: | ACYP2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ACYP2 antibody (CAB15636) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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