UniProt Protein Function: | ACP6: Hydrolyzes lysophosphatidic acid to monoacylglycerol. Belongs to the histidine acid phosphatase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Motility/polarity/chemotaxis; Mitochondrial; EC 3.1.3.2; Secreted; Phosphatase (non-protein); Cofactor and Vitamin Metabolism - riboflavin Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; mitochondrion Biological Process: phospholipid metabolic process |
NCBI Summary: | This gene encodes a member of the histidine acid phosphatase protein family. The encoded protein hydrolyzes lysophosphatidic acid, which is involved in G protein-coupled receptor signaling, lipid raft modulation, and in balancing lipid composition within the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2016] |
UniProt Code: | Q9NPH0 |
NCBI GenInfo Identifier: | 317373268 |
NCBI Gene ID: | 51205 |
NCBI Accession: | Q9NPH0.2 |
UniProt Secondary Accession: | Q9NPH0,Q59G61, Q5T490, Q6IAQ3, Q7LG81, Q9UIG6, |
UniProt Related Accession: | Q9NPH0 |
Molecular Weight: | 30,790 Da |
NCBI Full Name: | Lysophosphatidic acid phosphatase type 6 |
NCBI Synonym Full Names: | acid phosphatase 6, lysophosphatidic |
NCBI Official Symbol: | ACP6 |
NCBI Official Synonym Symbols: | LPAP; ACPL1; PACPL1 |
NCBI Protein Information: | lysophosphatidic acid phosphatase type 6 |
UniProt Protein Name: | Lysophosphatidic acid phosphatase type 6 |
UniProt Synonym Protein Names: | Acid phosphatase 6, lysophosphatidic; Acid phosphatase-like protein 1; PACPL1 |
Protein Family: | Lysophosphatidic acid phosphatase |
UniProt Gene Name: | ACP6 |
UniProt Entry Name: | PPA6_HUMAN |