Description
Antibody Name: | Anti-Acetyl-Histone H4-K5/K8/K12/K16 Antibody (CAB20764) |
Antibody SKU: | CAB20764 |
Antibody Size: | 50µL, 100µL |
Application: | Immunohistochemistry |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthetic acetylated peptide around K5/K8/K12/K16 of human Histone H4. |
Application: | Immunohistochemistry |
Recommended Dilution: | IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: |
Immunogen: | A synthetic acetylated peptide around K5/K8/K12/K16 of human Histone H4. |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Cellular Location: | |
Calculated MW: | 11kDa |
Observed MW: | Refer to figures |
Synonyms: | H4, H4/n, H4C1, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4F2, H4FN, FO108, H4-16, H4C11, H4C12, H4C13, H4C15, HIST2H4, HIST2H4A |
Background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. |
Anti-Acetyl-Histone H4-K5/K8/K12/K16 Antibody (CAB20764) |