Cell Biology Antibodies 11

Anti-ACAD9 Antibody (CAB7798)

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SKU:
CAB7798
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ACAD9 Antibody
Antibody SKU:CAB7798
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACAD9 (NP_054768.2).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse
Positive Samples:SKOV3, U-251MG, MCF7, 293T, NCI-H460, Mouse kidney, Mouse liver, Mouse brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACAD9 (NP_054768.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSGC GLFL RTTA AARA CRGL VVST ANRR LLRT SPPV RAFA KELF LGKI KKKE VFPF PEVS QDEL NEIN QFLG PVEK FFTE EVDS RKID QEGK IPDE TLEK LKSL GLFG LQVP EEYG GLGF SNTM YSRL GEII SMDG SITV TLAA HQAI GLKG IILA GTEE QKAK YLPK LASG EHIA AFCL TEPA SGSD AASI RSRA TLSE DKKH YILN GSKV WITN GGLA NIFT VFAK TEVV DSDG SVKD KITA FIVE RDFG GVTN GKPE DKLG IRGS NT
Gene ID:28976
Uniprot:Q9H845
Cellular Location:Mitochondrion
Calculated MW:68kDa
Observed MW:69kDa
Synonyms:ACAD9, NPD002
Background:This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.
UniProt Protein Function:ACAD9: Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA then on stearoyl-CoA. Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0). Belongs to the acyl-CoA dehydrogenase family.
UniProt Protein Details:

Protein type:EC 1.3.99.-; Mitochondrial; Oxidoreductase

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: dendrite; mitochondrial inner membrane; mitochondrion; nucleus

Molecular Function:acyl-CoA binding; acyl-CoA dehydrogenase activity; electron carrier activity; FAD binding; protein binding

Biological Process: fatty acid beta-oxidation using acyl-CoA dehydrogenase; lipid homeostasis; mitochondrial respiratory chain complex I assembly

Disease: Acyl-coa Dehydrogenase Family, Member 9, Deficiency Of

NCBI Summary:This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
UniProt Code:Q9H845
NCBI GenInfo Identifier:21361497
NCBI Gene ID:28976
NCBI Accession:
UniProt Secondary Accession:Q9H845,Q8WXX3, D3DNB8,
UniProt Related Accession:Q9H845
Molecular Weight:69kDa
NCBI Full Name:acyl-CoA dehydrogenase family member 9, mitochondrial
NCBI Synonym Full Names:acyl-CoA dehydrogenase family member 9
NCBI Official Symbol:ACAD9  
NCBI Official Synonym Symbols:NPD002  
NCBI Protein Information:acyl-CoA dehydrogenase family member 9, mitochondrial
UniProt Protein Name:Acyl-CoA dehydrogenase family member 9, mitochondrial
Protein Family:Acyl-CoA dehydrogenase family
UniProt Gene Name:ACAD9  
UniProt Entry Name:ACAD9_HUMAN
Anti-ACAD9 Antibody (CAB7798)Western blot analysis of extracts of various cell lines, using ACAD9 antibody (CAB7798) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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