Name: Anti-ACAA1 Antibody (CAB15018)
Brand: Metabolism Antibodies 1
SKU: CAB15018
Availability: OutOfStock

Antibody Name:	Anti-ACAA1 Antibody
Antibody SKU:	CAB15018
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 27-300 of human ACAA1 (NP_001598.1).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 27-300 of human ACAA1 (NP_001598.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	LSGA PQAS AADV VVVH GRRT AICR AGRG GFKD TTPD ELLS AVMT AVLK DVNL RPEQ LGDI CVGN VLQP GAGA IMAR IAQF LSDI PETV PLST VNRQ CSSG LQAV ASIA GGIR NGSY DIGM ACGV ESMS LADR GNPG NITS RLME KEKA RDCL IPMG ITSE NVAE RFGI SREK QDTF ALAS QQKA ARAQ SKGC FQAE IVPV TTTV HDDK GTKR SITV TQDE GIRP STTM EGLA KLKP AFKK DGST TAGN SSQV SDGA AAIL LARR SKAE ELGL PI
Gene ID:	30
Uniprot:	P09110
Cellular Location:	Peroxisome
Calculated MW:	34kDa/44kDa
Observed MW:	Refer to figures

Synonyms:	ACAA1, ACAA, PTHIO, THIO
Background:	This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants.

UniProt Protein Function:	ACAA1: an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
UniProt Protein Details:	Protein type:Lipid Metabolism - unsaturated fatty acid biosynthesis; Lipid Metabolism - fatty acid; Acetyltransferase; EC 2.3.1.16; Amino Acid Metabolism - valine, leucine and isoleucine degradation Chromosomal Location of Human Ortholog: 3p22.2 Cellular Component: peroxisomal matrix; membrane; intracellular membrane-bound organelle; peroxisome Molecular Function:palmitoyl-CoA oxidase activity; protein binding; acetyl-CoA C-acyltransferase activity Biological Process: fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid beta-oxidation; very-long-chain fatty acid metabolic process; bile acid metabolic process; unsaturated fatty acid metabolic process; cellular lipid metabolic process Disease: D-bifunctional Protein Deficiency
NCBI Summary:	This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
UniProt Code:	P09110
NCBI GenInfo Identifier:	135751
NCBI Gene ID:	30
NCBI Accession:	P09110.2
UniProt Secondary Accession:	P09110,Q96CA6, G5E935,
UniProt Related Accession:	P09110
Molecular Weight:	424
NCBI Full Name:	3-ketoacyl-CoA thiolase, peroxisomal
NCBI Synonym Full Names:	acetyl-CoA acyltransferase 1
NCBI Official Symbol:	ACAA1
NCBI Official Synonym Symbols:	ACAA; THIO; PTHIO
NCBI Protein Information:	3-ketoacyl-CoA thiolase, peroxisomal; beta-ketothiolase; peroxisomal 3-oxoacyl-CoA thiolase; acetyl-Coenzyme A acyltransferase 1; peroxisomal 3-oxoacyl-Coenzyme A thiolase
UniProt Protein Name:	3-ketoacyl-CoA thiolase, peroxisomal
UniProt Synonym Protein Names:	Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase
UniProt Gene Name:	ACAA1
UniProt Entry Name:	THIK_HUMAN