Cell Biology Antibodies 13
Anti-ABLIM3 Antibody (CAB17643)
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- SKU:
- CAB17643
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ABLIM3 Antibody |
| Antibody SKU: | CAB17643 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-520 of human ABLIM3 (NP_001287957.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse lung, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-520 of human ABLIM3 (NP_001287957.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TSED ISQT SKYS PIYS PDPY YASE SEYW TYHG SPKV PRAR RFSS GGEE DDFD RSMH KLQS GIGR LILK EEMK ARSS SYAD PWTP PRSS TSSR EALH TAGY EMSL NGSP RSHY LADS DPLI SKSA SLPA YRRN GLHR TPSA DLFH YDSM NAVN WGMR EYKI YPYE LLLV TTR |
| Gene ID: | 22885 |
| Uniprot: | O94929 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 78kDa |
 | Western blot - ABLIM3 Rabbit pAb (CAB17643) |
| Synonyms: | HMFN1661, ABLIM3 |
| Background: | This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal LIM domain and a C-terminal dematin-like domain. The encoded protein interacts with actin filaments and may be a component of adherens junctions in several cell types. A variant of this gene may be associated with pain sensitivity in male human patients. [provided by RefSeq, Sep 2016] |
| UniProt Protein Function: | ABLIM3: May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis; Actin-binding Chromosomal Location of Human Ortholog: 5q32 Cellular Component: lamellipodium; stress fiber Molecular Function:protein binding Biological Process: cilium biogenesis; lamellipodium biogenesis |
| NCBI Summary: | The LIM domain is a double zinc finger structure that promotes protein-protein interactions. LIM domain proteins, such as ABLIM3, play roles in embryonic development, cell lineage determination, and cancer (Krupp et al., 2006 [PubMed 16328021]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | O94929 |
| NCBI GenInfo Identifier: | 56404448 |
| NCBI Gene ID: | 22885 |
| NCBI Accession: | O94929.3 |
| UniProt Secondary Accession: | O94929,Q19VH3, Q658S1, Q68CI5, Q9BV32, A8K121, |
| UniProt Related Accession: | O94929 |
| Molecular Weight: | 19,695 Da |
| NCBI Full Name: | Actin-binding LIM protein 3 |
| NCBI Synonym Full Names: | actin binding LIM protein family member 3 |
| NCBI Official Symbol: | ABLIM3 |
| NCBI Official Synonym Symbols: | HMFN1661 |
| NCBI Protein Information: | actin-binding LIM protein 3 |
| UniProt Protein Name: | Actin-binding LIM protein 3 |
| UniProt Synonym Protein Names: | Actin-binding LIM protein family member 3 |
| Protein Family: | Actin-binding LIM protein |
| UniProt Gene Name: | ABLIM3 |
| UniProt Entry Name: | ABLM3_HUMAN |
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