Cell Biology Antibodies 16
Anti-ABHD4 Antibody (CAB17751)
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- SKU:
- CAB17751
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ABHD4 Antibody |
| Antibody SKU: | CAB17751 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 223-342 of human ABHD4 (NP_071343.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 223-342 of human ABHD4 (NP_071343.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PDFK RKFA DFFE DDTI SEYI YHCN AQNP SGET AFKA MMES FGWA RRPM LERI HLIR KDVP ITMI YGSD TWID TSTG KKVK MQRP DSYV RDME IKGA SHHV YADQ PHIF NAVV EEIC DSVD |
| Gene ID: | 63874 |
| Uniprot: | Q8TB40 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 39kDa |
 | Western blot - ABHD4 Rabbit pAb (CAB17751) |
| Synonyms: | ABH4, ABHD4 |
| Background: |
| UniProt Protein Function: | ABHD4: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine. Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily. |
| UniProt Protein Details: | Protein type:Hydrolase; EC 3.1.1.- Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: endoplasmic reticulum membrane; lipid particle Molecular Function:hydrolase activity Biological Process: lipid metabolic process; phospholipid metabolic process; sequestering of lipid |
| UniProt Code: | Q8TB40 |
| NCBI GenInfo Identifier: | 74762601 |
| NCBI Gene ID: | 63874 |
| NCBI Accession: | Q8TB40.1 |
| UniProt Secondary Accession: | Q8TB40,Q9H9E0, B4DDH7, |
| UniProt Related Accession: | Q8TB40 |
| Molecular Weight: | 20,239 Da |
| NCBI Full Name: | Protein ABHD4 |
| NCBI Synonym Full Names: | abhydrolase domain containing 4 |
| NCBI Official Symbol: | ABHD4 |
| NCBI Official Synonym Symbols: | ABH4 |
| NCBI Protein Information: | protein ABHD4 |
| UniProt Protein Name: | Protein ABHD4 |
| UniProt Synonym Protein Names: | Alpha/beta hydrolase domain-containing protein 4 |
| Protein Family: | Protein |
| UniProt Gene Name: | ABHD4 |
| UniProt Entry Name: | ABHD4_HUMAN |
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