Signal Transduction Antibodies 3

Anti-ABCC3 Antibody (CAB9849)

(No reviews yet) Write a Review
SKU:
CAB9849
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-ABCC3 Antibody
Antibody SKU:CAB9849
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 830-950 of human ABCC3 (NP_003777.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human
Positive Samples:HepG2, SW620
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 830-950 of human ABCC3 (NP_003777.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SEMG PYPA LLQR NGSF ANFL CNYA PDED QGHL EDSW TALE GAED KEAL LIED TLSN HTDL TDND PVTY VVQK QFMR QLSA LSSD GEGQ GRPV PRRH LGPS EKVQ VTEA KADG ALTQ EEKA A
Gene ID:8714
Uniprot:O15438
Cellular Location:Membrane, Multi-pass membrane protein
Calculated MW:55kDa/64kDa/137kDa/169kDa/174kDa
Observed MW:169kDa
Synonyms:ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2
Background:The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
NCBI Summary:The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
UniProt Code:O15438
NCBI GenInfo Identifier:15559191
NCBI Gene ID:8714
NCBI Accession:CAC69553.1
UniProt Related Accession:O15438
Molecular Weight:167,827 Da
NCBI Full Name:multidrug resistance associated protein
NCBI Synonym Full Names:ATP binding cassette subfamily C member 3
NCBI Official Symbol:ABCC3  
NCBI Official Synonym Symbols:MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757  
NCBI Protein Information:canalicular multispecific organic anion transporter 2
UniProt Protein Name:Multidrug resistance associated protein
UniProt Synonym Protein Names:Multidrug resistance associated protein
Protein Family:MIP-related peptides
UniProt Gene Name:MRP3  
Anti-ABCC3 Polyclonal Antibody (CAB9849)Western blot analysis of extracts of various cell lines, using ABCC3 antibody (CAB9849) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
Anti-ABCC3 Polyclonal Antibody (CAB9849)Immunohistochemistry of paraffin-embedded human prostate using ABCC3 antibody (CAB9849) at dilution of 1:100 (40x lens).
View AllClose

0 Reviews

View AllClose

Related Products