Cell Biology Antibodies 15
Anti-ABCC10 Antibody (CAB18520)
- SKU:
- CAB18520
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ABCC10 Antibody |
| Antibody SKU: | CAB18520 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ABCC10. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: |
| Immunogen: | Recombinant protein of human ABCC10. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 89845 |
| Uniprot: | Q5T3U5 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | Refer to figures |
| Synonyms: | EST182763, MRP7, SIMRP7, ABCC10 |
| Background: |
| UniProt Protein Function: | ABCC10: ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, ABC family Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: lysosomal membrane; integral to membrane; plasma membrane Molecular Function:ATPase activity, coupled to transmembrane movement of substances; ATP binding Biological Process: metabolic process; transmembrane transport |
| NCBI Summary: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010] |
| UniProt Code: | Q5T3U5 |
| NCBI GenInfo Identifier: | 312176403 |
| NCBI Gene ID: | 89845 |
| NCBI Accession: | NP_001185863.1 |
| UniProt Secondary Accession: | Q5T3U5,Q8NHX7, Q9H7N2, Q9NXY3, Q9UF48, |
| UniProt Related Accession: | Q5T3U5 |
| Molecular Weight: | 161,629 Da |
| NCBI Full Name: | multidrug resistance-associated protein 7 isoform MRP7 |
| NCBI Synonym Full Names: | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 |
| NCBI Official Symbol: | ABCC10 |
| NCBI Official Synonym Symbols: | MRP7; SIMRP7; EST182763 |
| NCBI Protein Information: | multidrug resistance-associated protein 7; ATP-binding cassette sub-family C member 10 |
| UniProt Protein Name: | Multidrug resistance-associated protein 7 |
| UniProt Synonym Protein Names: | ATP-binding cassette sub-family C member 10 |
| UniProt Gene Name: | ABCC10 |
| UniProt Entry Name: | MRP7_HUMAN |