Anti-ABCA8 Antibody (CAB20553)
- SKU:
- CAB20553
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Description
| Product Name: | ABCA8 Rabbit pAb |
| Product Code: | CAB20553 |
| Size: | 50uL, 100uL |
| Applications: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human ABCA8. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa, HepG2, U-251MG |
| Immunogen: | Recombinant protein of human ABCA8. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10351 |
| Uniprot: | O94911 |
| Calculated MW: | 183kDa |
| Observed MW: | 180KDa |
| UniProt Protein Function: | ABCA8: ATP-dependent lipophilic drug transporter. Belongs to the ABC transporter superfamily. ABCA family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Hydrolase; Mitochondrial; Transporter, ABC family; Transporter Chromosomal Location of Human Ortholog: 17q24 Cellular Component: mitochondrial inner membrane; plasma membrane; integral to membrane Molecular Function: ATPase activity, coupled to transmembrane movement of substances; ATP binding Biological Process: metabolic process; transport; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| UniProt Code: | O94911 |
| NCBI GenInfo Identifier: | 115503766 |
| NCBI Gene ID: | 10351 |
| NCBI Accession: | O94911.3 |
| UniProt Secondary Accession: | O94911,Q86WW0, A1L3U3, C9JQE6 |
| UniProt Related Accession: | O94911 |
| Molecular Weight: | 183,677 Da |
| NCBI Full Name: | ATP-binding cassette sub-family A member 8 |
| NCBI Synonym Full Names: | ATP-binding cassette, sub-family A (ABC1), member 8 |
| NCBI Official Symbol: | ABCA8 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | ATP-binding cassette sub-family A member 8 |
| UniProt Protein Name: | ATP-binding cassette sub-family A member 8 |
| UniProt Synonym Protein Names: | |
| Protein Family: | ABC transporter A family |
| UniProt Gene Name: | ABCA8 |
| UniProt Entry Name: | ABCA8_HUMAN |
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