Cardiovascular Antibodies
Anti-AAMP Antibody (CAB3283)
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- SKU:
- CAB3283
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Description
| Antibody Name: | Anti-AAMP Antibody |
| Antibody SKU: | CAB3283 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 85-434 of human AAMP (NP_001078.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:1000 - 1:3000 IF 1:100 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A375, HepG2, 293T, MCF7, Mouse liver, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 85-434 of human AAMP (NP_001078.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VTFA LHSA SVFC VSLD PKTN TLAV TGGE DDKA FVWR LSDG ELLF ECAG HKDS VTCA GFSH DSTL VATG DMSG LLKV WQVD TKEE VWSF EAGD LEWM EWHP RAPV LLAG TADG NTWM WKVP NGDC KTFQ GPNC PATC GRVL PDGK RAVV GYED GTIR IWDL KQGS PIHV LKGT EGHQ GPLT CVAA NQDG SLIL TGSV DCQA KLVS ATTG KVVG VFRP ETVA SQPS LGEG EESE SNSV ESLG FCSV MPLA AVGY LDGT LAIY DLAT QTLR HQCQ HQSG IVQL LWEA GTAV VYTC SLDG IVRL WDAR TGRL LTDY RGHT AEIL DFAL SKDA SLVV TTSG DHKA KVFC VQRP DR |
| Gene ID: | 14 |
| Uniprot: | Q13685 |
| Cellular Location: | Cell membrane, Cytoplasm |
| Calculated MW: | 46kDa |
| Observed MW: | 47kDa |
| Synonyms: | AAMP |
| Background: | The gene is a member of the immunoglobulin superfamily. The encoded protein is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. The encoded protein can bind to heparin and may mediate heparin-sensitive cell adhesion. |
| UniProt Protein Function: | AAMP: Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Cell development/differentiation; Cell surface Chromosomal Location of Human Ortholog: 2q35 Cellular Component: cell surface; cytoplasm; plasma membrane Molecular Function:heparin binding Biological Process: smooth muscle cell migration; angiogenesis; cell differentiation |
| NCBI Summary: | The gene is a member of the immunoglobulin superfamily. The encoded protein is associated with angiogenesis, with potential roles in endothelial tube formation and the migration of endothelial cells. It may also regulate smooth muscle cell migration via the RhoA pathway. The encoded protein can bind to heparin and may mediate heparin-sensitive cell adhesion. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q13685 |
| NCBI GenInfo Identifier: | 62906874 |
| NCBI Gene ID: | 14 |
| NCBI Accession: | Q13685.2 |
| UniProt Secondary Accession: | Q13685,Q8WUJ9, Q96H92, |
| UniProt Related Accession: | Q13685 |
| Molecular Weight: | 434 |
| NCBI Full Name: | Angio-associated migratory cell protein |
| NCBI Synonym Full Names: | angio-associated, migratory cell protein |
| NCBI Official Symbol: | AAMP |
| NCBI Protein Information: | angio-associated migratory cell protein |
| UniProt Protein Name: | Angio-associated migratory cell protein |
| Protein Family: | Angio-associated migratory cell protein |
| UniProt Gene Name: | AAMP |
| UniProt Entry Name: | AAMP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using AAMP antibody (CAB3283) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunofluorescence analysis of 293T cells using AAMP antibody (CAB3283) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
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