Signal Transduction Antibodies 1

Anti-A4GNT Antibody (CAB12366)

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SKU:
CAB12366
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-A4GNT Antibody
Antibody SKU:CAB12366
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human A4GNT (NP_057245.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:SGC-7901, 293T, LO2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human A4GNT (NP_057245.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRKE LQLS LSVT LLLV CGFL YQFT LKSS CLFC LPSF KSHQ GLEA LLSH RRGI VFLE TSER MEPP HLVS CSVE SAAK IYPE WPVV FFMK GLTD STPM PSNS TYPA FSFL SAID NVFL FPLD MKRL LEDT PLFS WYNQ INAS AERN WLHI SSDA SRLA IIWK YGGI YMDT DVIS IRPI PEEN FLAA QASR YSSN GIFG FLPH HPFL WECM ENFV EHYN SAIW GNQG PELM TRML RVWC KLED FQEV SDLR CLNI SFLH PQRF YPIS YREW RRYY EVWD TEPS FNVS YALH LWNH MNQE GRAV IRGS NTLV ENLY RKHC PRTY RDLI KGPE GSVT GELG PGNK
Gene ID:51146
Uniprot:Q9UNA3
Cellular Location:Golgi apparatus membrane, Single-pass type II membrane protein
Calculated MW:39kDa
Observed MW:37kDa
Synonyms:A4GNT, alpha4GnT, alpha-1
Background:This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane.
UniProt Protein Function:A4GNT: Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O- glycans. Belongs to the glycosyltransferase 32 family.
UniProt Protein Details:

Protein type:EC 2.4.1.-; Membrane protein, integral; Transferase

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: Golgi membrane; membrane

Molecular Function:acetylglucosaminyltransferase activity

Biological Process: carbohydrate metabolic process; glycoprotein biosynthetic process; O-glycan processing; protein amino acid O-linked glycosylation

NCBI Summary:This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. It forms a unique glycan, GlcNAcalpha1-->4Galbeta-->R and is largely associated with the Golgi apparatus membrane. [provided by RefSeq, Jul 2008]
UniProt Code:Q9UNA3
NCBI GenInfo Identifier:25452797
NCBI Gene ID:51146
NCBI Accession:Q9UNA3.1
UniProt Secondary Accession:Q9UNA3,Q0VDK1, Q0VDK2,
UniProt Related Accession:Q9UNA3
Molecular Weight:39kDa
NCBI Full Name:Alpha-1,4-N-acetylglucosaminyltransferase
NCBI Synonym Full Names:alpha-1,4-N-acetylglucosaminyltransferase
NCBI Official Symbol:A4GNT  
NCBI Official Synonym Symbols:alpha4GnT  
NCBI Protein Information:alpha-1,4-N-acetylglucosaminyltransferase
UniProt Protein Name:Alpha-1,4-N-acetylglucosaminyltransferase
Protein Family:Alpha-1,4-N-acetylglucosaminyltransferase
UniProt Gene Name:A4GNT  
Anti-A4GNT Antibody (CAB12366)Western blot analysis of extracts of various cell lines, using A4GNT antibody (CAB12366) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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