Anti-5HT7 Receptor Antibody (CAB19706)
- SKU:
- CAB19706
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- 5-HT7
Description
| Product Name: | 5HT7 Receptor Rabbit mAb |
| Product Code: | CAB19706 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | 5-HT7 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human 5HT7 Receptor |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | C6, SH-SY5Y, U-87MG, Mouse testis, Mouse brain, Mouse spleen, Rat testis, Rat brain |
| Immunogen: | A synthesized peptide derived from human 5HT7 Receptor |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3363 |
| Uniprot: | P34969 |
| Calculated MW: | 54kDa |
| Observed MW: | 54KDa |
| UniProt Protein Function: | 5-HT(7): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCRChromosomal Location of Human Ortholog: 10q21-q24Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: serotonin receptor activityBiological Process: blood circulation; circadian rhythm; G-protein signaling, coupled to cyclic nucleotide second messenger; serotonin receptor signaling pathway; smooth muscle contraction; synaptic transmission; vasoconstriction |
| UniProt Protein Details: | |
| NCBI Summary: | The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P34969 |
| NCBI GenInfo Identifier: | 8488960 |
| NCBI Gene ID: | 3363 |
| NCBI Accession: | P34969.2 |
| UniProt Secondary Accession: | P34969,P78336, P78372, P78516, Q5VX01, Q5VX02, Q5VX03 B5BUP6 |
| UniProt Related Accession: | P34969 |
| Molecular Weight: | 47,984 Da |
| NCBI Full Name: | 5-hydroxytryptamine receptor 7 |
| NCBI Synonym Full Names: | 5-hydroxytryptamine receptor 7 |
| NCBI Official Symbol: | HTR7 |
| NCBI Official Synonym Symbols: | 5-HT7 |
| NCBI Protein Information: | 5-hydroxytryptamine receptor 7 |
| UniProt Protein Name: | 5-hydroxytryptamine receptor 7 |
| UniProt Synonym Protein Names: | 5-HT-X; Serotonin receptor 7 |
| Protein Family: | 5-hydroxytryptamine receptor |
| UniProt Gene Name: | HTR7 |
| UniProt Entry Name: | 5HT7R_HUMAN |
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