| UniProt Protein Function: | 5-HT(7): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCRChromosomal Location of Human Ortholog: 10q21-q24Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: serotonin receptor activityBiological Process: blood circulation; circadian rhythm; G-protein signaling, coupled to cyclic nucleotide second messenger; serotonin receptor signaling pathway; smooth muscle contraction; synaptic transmission; vasoconstriction |
| UniProt Protein Details: | |
| NCBI Summary: | The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P34969 |
| NCBI GenInfo Identifier: | 8488960 |
| NCBI Gene ID: | 3363 |
| NCBI Accession: | P34969.2 |
| UniProt Secondary Accession: | P34969,P78336, P78372, P78516, Q5VX01, Q5VX02, Q5VX03 B5BUP6 |
| UniProt Related Accession: | P34969 |
| Molecular Weight: | 47,984 Da |
| NCBI Full Name: | 5-hydroxytryptamine receptor 7 |
| NCBI Synonym Full Names: | 5-hydroxytryptamine receptor 7 |
| NCBI Official Symbol: | HTR7 |
| NCBI Official Synonym Symbols: | 5-HT7 |
| NCBI Protein Information: | 5-hydroxytryptamine receptor 7 |
| UniProt Protein Name: | 5-hydroxytryptamine receptor 7 |
| UniProt Synonym Protein Names: | 5-HT-X; Serotonin receptor 7 |
| Protein Family: | 5-hydroxytryptamine receptor |
| UniProt Gene Name: | HTR7 |
| UniProt Entry Name: | 5HT7R_HUMAN |
