Description
system_update_altDatasheet
| SKU: | HDLA028 |
| Size: | 100 µg |
| Clonality: | Monoclonal |
| Clone: | DM66 |
| Synonyms: | TNFRSF9, 4-1BB, CD137, CDw137, ILA |
| Applications: | ELISA, Flow Cyt |
| Recommended Dilution: | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: | Rabbit |
| Isotype: | Rabbit IgG |
| Reactivity: | Human |
| Purification Method: | Purified from cell culture supernatant by affinity chromatography |
| Formulation: | Powder |
| Buffer: | 1XPBS |
| Storage: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
| Usage: | Research use only |
| Background: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |
