Antibody Name:	ANP32C Antibody (PACO18652)
Antibody SKU:	PACO18652
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human ANP32C

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18652(ANP32C Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18652(ANP32C Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid, sequence to PP32 and are part of the same acid, c nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid, region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns.

Synonyms:

acid, c (leucine-rich) nuclear phosphoprotein 32 family, member C

UniProt Protein Function:	ANP32C: Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]Chromosomal Location of Human Ortholog: 4q32.3
UniProt Protein Details:
NCBI Summary:	Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]
UniProt Code:	O43423
NCBI GenInfo Identifier:	26390773
NCBI Gene ID:	23520
NCBI Accession:	O43423.1
UniProt Secondary Accession:	O43423,Q4W5F9
UniProt Related Accession:	O43423
Molecular Weight:	26,762 Da
NCBI Full Name:	Acidic leucine-rich nuclear phosphoprotein 32 family member C
NCBI Synonym Full Names:	acidic nuclear phosphoprotein 32 family member C
NCBI Official Symbol:	ANP32C
NCBI Official Synonym Symbols:	PP32R1
NCBI Protein Information:	acidic leucine-rich nuclear phosphoprotein 32 family member C
UniProt Protein Name:	Acidic leucine-rich nuclear phosphoprotein 32 family member C
UniProt Synonym Protein Names:	Phosphoprotein 32-related protein 1; Tumorigenic protein pp32r1
Protein Family:	Acidic leucine-rich nuclear phosphoprotein 32 family
UniProt Gene Name:	ANP32C
UniProt Entry Name:	AN32C_HUMAN