ANO7 Antibody (PACO23753)
- SKU:
- PACO23753
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ANO7 Antibody (PACO23753) |
| Antibody SKU: | PACO23753 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from C-terminal of human TM16G. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from LOVO cells, using TM16G antiobdy. |
 | Immunofluorescence analysis of HepG2 cells, using TM16G antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using TM16G antibody. |
| Background: | Does not exhibit calcium-activated chloride channel (CaCC) activity. May play a role in cell-cell interactions. |
| Synonyms: | New gene expressed in prostate; Prostate cancer-associated protein 5; IPCA-5; Dresden-transmembrane protein of the prostate; D-TMPP |
| UniProt Protein Function: | ANO7: May act as a calcium-activated chloride channel. May play a role in cell-cell interactions. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, ion channel; Channel, chloride; Calcium-binding; Membrane protein, integral; Transporter; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2q37.3Cellular Component: endoplasmic reticulum; integral to membrane; plasma membrane; intracellular; nucleus; cytosol; cell junctionMolecular Function: phospholipid scramblase activity; intracellular calcium activated chloride channel activityBiological Process: chloride transport; lipid transport; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q6IWH7 |
| NCBI GenInfo Identifier: | 48717269 |
| NCBI Gene ID: | 50636 |
| NCBI Accession: | NP_001001666.1 |
| UniProt Secondary Accession: | Q6IWH7,Q6IWH6 |
| UniProt Related Accession: | Q6IWH7 |
| Molecular Weight: | 105,532 Da |
| NCBI Full Name: | anoctamin-7 isoform NGEP-short |
| NCBI Synonym Full Names: | anoctamin 7 |
| NCBI Official Symbol: | ANO7 |
| NCBI Official Synonym Symbols: | NGEP; DTMPP; IPCA5; D-TMPP; IPCA-5; PCANAP5; TMEM16G; PCANAP5L |
| NCBI Protein Information: | anoctamin-7; transmembrane protein 16G; prostate cancer associated protein 5; Dresden-transmembrane protein of the prostate |
| UniProt Protein Name: | Anoctamin-7 |
| UniProt Synonym Protein Names: | Dresden transmembrane protein of the prostate; D-TMPP; IPCA-5; New gene expressed in prostate; Prostate cancer-associated protein 5; Transmembrane protein 16G |
| Protein Family: | Anoctamin |
| UniProt Gene Name: | ANO7 |
| UniProt Entry Name: | ANO7_HUMAN |
| Antibodies |
| ANO7 Antibody (PACO02953) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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