Description
| Antibody Name: | ANO7 Antibody |
| Antibody SKU: | PACO02953 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human NGEP. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ANO7; NGEP; PCANAP5; TMEM16G; Anoctamin-7; Dresden transmembrane protein of the prostate; D-TMPP; IPCA-5; New gene expressed in prostate; Prostate cancer-associated protein 5; Transmembrane protein 16G |
| UniProt Protein Function: | ANO7: May act as a calcium-activated chloride channel. May play a role in cell-cell interactions. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, ion channel; Channel, chloride; Calcium-binding; Membrane protein, integral; Transporter; Membrane protein, multi-passChromosomal Location of Human Ortholog: 2q37.3Cellular Component: endoplasmic reticulum; integral to membrane; plasma membrane; intracellular; nucleus; cytosol; cell junctionMolecular Function: phospholipid scramblase activity; intracellular calcium activated chloride channel activityBiological Process: chloride transport; lipid transport; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011] |
| UniProt Code: | Q6IWH7 |
| NCBI GenInfo Identifier: | 48717269 |
| NCBI Gene ID: | 50636 |
| NCBI Accession: | NP_001001666.1 |
| UniProt Secondary Accession: | Q6IWH7,Q6IWH6 |
| UniProt Related Accession: | Q6IWH7 |
| Molecular Weight: | 105,532 Da |
| NCBI Full Name: | anoctamin-7 isoform NGEP-short |
| NCBI Synonym Full Names: | anoctamin 7 |
| NCBI Official Symbol: | ANO7 |
| NCBI Official Synonym Symbols: | NGEP; DTMPP; IPCA5; D-TMPP; IPCA-5; PCANAP5; TMEM16G; PCANAP5L |
| NCBI Protein Information: | anoctamin-7; transmembrane protein 16G; prostate cancer associated protein 5; Dresden-transmembrane protein of the prostate |
| UniProt Protein Name: | Anoctamin-7 |
| UniProt Synonym Protein Names: | Dresden transmembrane protein of the prostate; D-TMPP; IPCA-5; New gene expressed in prostate; Prostate cancer-associated protein 5; Transmembrane protein 16G |
| Protein Family: | Anoctamin |
| UniProt Gene Name: | ANO7 |
| UniProt Entry Name: | ANO7_HUMAN |