ANO4 Antibody (PACO35890)
- SKU:
- PACO35890
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ANO4 Antibody (PACO35890) |
| Antibody SKU: | PACO35890 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Anoctamin-4 protein (1-200AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human lung cancer using PACO35890 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO35890 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO35890 at dilution of 1:100. |
| Background: | Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide. Does not exhibit calcium-activated chloride channel (CaCC) activity. |
| Synonyms: | Anoctamin-4 (Transmembrane protein 16D), ANO4, TMEM16D |
| UniProt Protein Function: | ANO4: May act as a calcium-activated chloride channel. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, ion channel; Transporter; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 12q23.1Cellular Component: intracellular; plasma membraneMolecular Function: intracellular calcium activated chloride channel activityBiological Process: chloride transport |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q32M45 |
| NCBI GenInfo Identifier: | 115344372 |
| NCBI Gene ID: | 121601 |
| NCBI Accession: | BC109308 |
| UniProt Secondary Accession: | Q32M45,Q8NAJ0, Q8NB39, Q8NB53 |
| UniProt Related Accession: | Q32M45 |
| Molecular Weight: | 55,719 Da |
| NCBI Full Name: | Homo sapiens anoctamin 4, mRNA |
| NCBI Synonym Full Names: | anoctamin 4 |
| NCBI Official Symbol: | ANO4 |
| NCBI Official Synonym Symbols: | TMEM16D |
| NCBI Protein Information: | anoctamin-4 |
| UniProt Protein Name: | Anoctamin-4 |
| UniProt Synonym Protein Names: | Transmembrane protein 16D |
| Protein Family: | Anoctamin |
| UniProt Gene Name: | ANO4 |
| UniProt Entry Name: | ANO4_HUMAN |
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