Annexin A6/Annexin VI Monoclonal Antibody
- SKU:
- CAB22038
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | Annexin A6/Annexin VI Monoclonal Antibody |
| Product Code: | CAB22038 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54613 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:9000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, HeLa, C2C12, Mouse heart, PC-12, C6 |
| Cellular Location: | Cytoplasm, Melanosome |
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 324-673 of human Annexin A6/Annexin VI (NP_001146.2). |
| Sequence: | DDDAA GQFFP EAAQV AYQMW ELSAV ARVEL KGTVR PANDF NPDAD AKALR KAMKG LGTDE DTIID IITHR SNVQR QQIRQ TFKSH FGRDL MTDLK SEISG DLARL ILGLM MPPAH YDAKQ LKKAM EGAGT DEKAL IEILA TRTNA EIRAI NEAYK EDYHK SLEDA LSSDT SGHFR RILIS LATGH REEGG ENLDQ AREDA QVAAE ILEIA DTPSG DKTSL ETRFM TILCT RSYPH LRRVF QEFIK MTNYD VEHTI KKEMS GDVRD AFVAI VQSVK NKPLF FADKL YKSMK GAGTD EKTLT RIMVS RSEID LLNIR REFIE KYDKS LHQAI EGDTS GDFLK ALLAL CGGED |
| Synonyms: | p68, p70, ANX6, CBP68, CPB-II |
| Calculated MW: | 76kDa |
| Observed MW: | 72kDa |
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