Description
Product Name: | Annexin A2 Monoclonal Antibody |
Product Code: | CAB23279 |
Reactivity: | Human, Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59617 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, MCF7, LNcap(Low expression control), NIH/3T3 |
Cellular Location: | Melanosome, Secreted, basement membrane, extracellular matrix, extracellular space |
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Annexin A2 expression has been found to correlate with resistance to treatment against various cancer forms.
Immunogen: | Recombinant protein of human Annexin A2. |
Sequence: | MSTVH EILCK LSLEG DHSTP PSAYG SVKAY TNFDA ERDAL NIETA IKTKG VDEVT IVNIL TNRSN AQRQD IAFAY QRRTK KELAS ALKSA LSGHL ETVIL |
Synonyms: | P36, ANX2, LIP2, LPC2, CAL1H, LPC2D, ANX2L4, PAP-IV, HEL-S-270 |
Calculated MW: | 39kDa |
Observed MW: | 38kDa |