ANKS6 Antibody (PACO46594)
- SKU:
- PACO46594
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ANKS6 Antibody (PACO46594) |
| Antibody SKU: | PACO46594 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ankyrin repeat and SAM domain-containing protein 6 protein (1-132AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO46594 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO46594 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Required for renal function. |
| Synonyms: | Ankyrin repeat and SAM domain-containing protein 6 (Ankyrin repeat domain-containing protein 14) (SamCystin) (Sterile α motif domain-containing protein 6) (SAM domain-containing protein 6), ANKS6, ANKRD14 PKDR1 SAMD6 |
| UniProt Protein Function: | ANKS6: Required for renal function. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 9q22.33Disease: Nephronophthisis 16 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein containing multiple ankyrin repeats and a SAM domain. It is thought that this protein may localize to the proximal region of the primary cilium, and may play a role in renal and cardiovascular development. Mutations in this gene have been shown to cause a form of nephronophthisis (NPHP16), a chronic tubulo-interstitial nephritis. [provided by RefSeq, Jul 2015] |
| UniProt Code: | Q68DC2 |
| NCBI GenInfo Identifier: | 83305683 |
| NCBI Gene ID: | 203286 |
| NCBI Accession: | Q68DC2.2 |
| UniProt Secondary Accession: | Q68DC2,Q5VSL0, Q5VSL2, Q5VSL3, Q5VSL4, Q68DB8, Q6P2R2 Q8N9L6, Q96D62, A0SE62 |
| UniProt Related Accession: | Q68DC2 |
| Molecular Weight: | 92,347 Da |
| NCBI Full Name: | Ankyrin repeat and SAM domain-containing protein 6 |
| NCBI Synonym Full Names: | ankyrin repeat and sterile alpha motif domain containing 6 |
| NCBI Official Symbol: | ANKS6 |
| NCBI Official Synonym Symbols: | PKDR1; SAMD6; NPHP16; ANKRD14 |
| NCBI Protein Information: | ankyrin repeat and SAM domain-containing protein 6 |
| UniProt Protein Name: | Ankyrin repeat and SAM domain-containing protein 6 |
| UniProt Synonym Protein Names: | Ankyrin repeat domain-containing protein 14; SamCystin; Sterile alpha motif domain-containing protein 6; SAM domain-containing protein 6 |
| Protein Family: | Ankyrin repeat and SAM domain-containing protein |
| UniProt Gene Name: | ANKS6 |
| UniProt Entry Name: | ANKS6_HUMAN |
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