ANKRD54 Antibody (PACO15446)
- SKU:
- PACO15446
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ANKRD54 Antibody (PACO15446) |
| Antibody SKU: | PACO15446 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human ANKRD54 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15446(ANKRD54 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO15446(ANKRD54 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. Interacts (via ankyrin repeat region) with LYN (via SH3-domain) in an activation-independent status of LYN By similarity. Forms a multiprotein complex with LYN and HCLS1 By similarity. Interacts with TSN2, VAV1, DBNL AND LASP1. |
| Synonyms: | ankyrin repeat domain 54 |
| UniProt Protein Function: | ANKRD54: Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Cell cycle regulationChromosomal Location of Human Ortholog: 22q13.1Cellular Component: cytoplasm; midbody; nucleusMolecular Function: protein bindingBiological Process: positive regulation of erythrocyte differentiation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6NXT1 |
| NCBI GenInfo Identifier: | 125987708 |
| NCBI Gene ID: | 129138 |
| NCBI Accession: | Q6NXT1.2 |
| UniProt Secondary Accession: | Q6NXT1,Q6ZSB1, Q9UGV1 |
| UniProt Related Accession: | Q6NXT1 |
| Molecular Weight: | 18,254 Da |
| NCBI Full Name: | Ankyrin repeat domain-containing protein 54 |
| NCBI Synonym Full Names: | ankyrin repeat domain 54 |
| NCBI Official Symbol: | ANKRD54 |
| NCBI Official Synonym Symbols: | LIAR |
| NCBI Protein Information: | ankyrin repeat domain-containing protein 54 |
| UniProt Protein Name: | Ankyrin repeat domain-containing protein 54 |
| UniProt Synonym Protein Names: | Lyn-interacting ankyrin repeat protein |
| Protein Family: | Ankyrin repeat domain-containing protein |
| UniProt Gene Name: | ANKRD54 |
| UniProt Entry Name: | ANR54_HUMAN |
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