ANKRA2 Antibody (PACO18563)
- SKU:
- PACO18563
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ANKRA2 Antibody (PACO18563) |
| Antibody SKU: | PACO18563 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ANKRA2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18563(ANKRA2 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18563(ANKRA2 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This protein may facilitate endocytosis by linking megalin to components of the cytoskeleton or endocytic machinery. ANKRA2 is a megalin- and BKCa potassium channel-interacting factor. It is a protein known to interact with HDAC4 and HDAC5.ANKRA2 is important for transcriptional repression by AhRR. |
| Synonyms: | ankyrin repeat, family A (RFXANK-like), 2 |
| UniProt Protein Function: | May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5 (PubMed:25752541). May also regulate LRP2/megalin (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H9E1 |
| NCBI GenInfo Identifier: | 15991861 |
| NCBI Gene ID: | 57763 |
| NCBI Accession: | BC012917 |
| UniProt Secondary Accession: | Q9H9E1 |
| UniProt Related Accession: | Q9H9E1 |
| Molecular Weight: | 34,272 Da |
| NCBI Full Name: | Homo sapiens ankyrin repeat, family A (RFXANK-like), 2, mRNA |
| NCBI Synonym Full Names: | ankyrin repeat family A member 2 |
| NCBI Official Symbol: | ANKRA2 |
| NCBI Official Synonym Symbols: | ANKRA |
| NCBI Protein Information: | ankyrin repeat family A protein 2 |
| UniProt Protein Name: | Ankyrin repeat family A protein 2 |
| UniProt Synonym Protein Names: | RFXANK-like protein 2 |
| Protein Family: | Ankyrin repeat family A protein |
| UniProt Gene Name: | ANKRA2 |
| UniProt Entry Name: |
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