ANKMY2 Antibody (PACO15443)
- SKU:
- PACO15443
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ANKMY2 Antibody (PACO15443) |
| Antibody SKU: | PACO15443 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human ANKMY2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO15443(ANKMY2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15443(ANKMY2 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid, protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states. |
| Synonyms: | ankyrin repeat and MYND domain containing 2 |
| UniProt Protein Function: | ANKMY2: May be involved in the trafficking of signaling proteins to the cilia.Chromosomal Location of Human Ortholog: 7p21Cellular Component: ciliumMolecular Function: metal ion binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IV38 |
| NCBI GenInfo Identifier: | 28461129 |
| NCBI Gene ID: | 57037 |
| NCBI Accession: | NP_064715.1 |
| UniProt Secondary Accession: | Q8IV38,Q659G1, Q96BL3, A4D124 |
| UniProt Related Accession: | Q8IV38 |
| Molecular Weight: | 49,299 Da |
| NCBI Full Name: | ankyrin repeat and MYND domain-containing protein 2 |
| NCBI Synonym Full Names: | ankyrin repeat and MYND domain containing 2 |
| NCBI Official Symbol: | ANKMY2 |
| NCBI Official Synonym Symbols: | ZMYND20 |
| NCBI Protein Information: | ankyrin repeat and MYND domain-containing protein 2 |
| UniProt Protein Name: | Ankyrin repeat and MYND domain-containing protein 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ankyrin repeat and MYND domain-containing protein |
| UniProt Gene Name: | ANKMY2 |
| UniProt Entry Name: | ANKY2_HUMAN |
| Antibodies |
| ANKMY2 Antibody (PACO07737) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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